TRIO and F-actin binding protein

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Synonym

TRIO and F-actin binding protein, TRIO and F-actin-binding protein, dJ37E16.4, HRIHFB2122, TARA, Trio-associated repeat on actin, Tara, TRIOBP, DFNB28, FLJ39315, Protein Tara, KIAA1662

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:184 spine:- retina:- eye:229.20 artery/aorta:- vein:- lymphnode:80.90 peripheral blood:36.40 spleen:75.60 thymus:- bone marrow:78.70 adipose:80.70 bone:25.60 skin:57.60
GeneChip cerebrum:5.55 cerebellum:4.70 brain stem:5.72 corpus callosum/glia:6.32 pineal gland:- peripheral nerve:6.71 spine:6.34 retina:- eye:- artery/aorta:7.55 vein:7.39 lymphnode:7 peripheral blood:- spleen:8.24 thymus:6.83 bone marrow:7.11 adipose:7.78 bone:- skin:7.34
CAGE cerebrum:1.57 cerebellum:- brain stem:1.90 corpus callosum/glia:2.02 pineal gland:1.32 peripheral nerve:- spine:1.90 retina:- eye:- artery/aorta:3.21 vein:2.79 lymphnode:2.78 peripheral blood:- spleen:3.05 thymus:2.04 bone marrow:- adipose:2.70 bone:- skin:-
RNA-seq cerebrum:1.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.08 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.92 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:142.10 prostate:146.40 ovary:74.50 testis:13 heart:102.20 muscle:40.20 esophagus:- stomach:42.50 intestine:- colon:101.80     liver/hepato:21.10        lung:68.40    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:71.10 breast:37.20 salivary:-
GeneChip uterus:8.48 placenta:8.11 prostate:7.46 ovary:7.77 testis:7.19 heart:7.53 muscle:5.98 esophagus:8.55 stomach:7.77 intestine:7.39 colon:8.15 liver/hepato:6.77 lung:7.75 bladder:- kidney:7.09 pituitary:5.56 thyroid/parathyroid:7.87 adrenal gland:7.35 pancreas:6.89 breast:8.15 salivary:7.15
CAGE uterus:3.27 placenta:3.23 prostate:3.06 ovary:3.32 testis:2.43 heart:3.38 muscle:2.23 esophagus:3.22 stomach:- intestine:2.47 colon:3.35     liver/hepato:2.42    lung:3.21 bladder:3.07 kidney:2.58 pituitary:1.42 thyroid/parathyroid:2.53 adrenal gland:- pancreas:2.41 breast:3.75 salivary:2.50
RNA-seq uterus:- placenta:- prostate:3.91 ovary:4.18 testis:3.51 heart:3.06 muscle:1.63 esophagus:- stomach:- intestine:- colon:3.30     liver/hepato:1.46        lung:3.39    bladder:- kidney:3.07 pituitary:- thyroid/parathyroid:3.01 adrenal gland:3.45 pancreas:- breast:3.43 salivary:-

Gene Information

IDs

Refseq ID NM_007032
Gene ID 11078
Unigene ID Hs.533030
Probe set ID 210276_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100106
GTEx ID ENSG00000100106

Orthologous Gene

Mouse[4]  NM_001024716, NM_001039155, NM_001039156, NM_138579
Rat[4]  NM_001024716, NM_001039155, NM_001039156, NM_138579

Chromosomal Region

22q13.1  [38,093,011  -  38,172,563]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

8500161
8889548
9853615
10591208
11076863
11148140
11258795
12168954
12477932
14702039
15489334
15489336
16169070
16344560
16381901
16385457
16385458
17081983
17629495
18029348
18194665
19322201
19913121
19996280
20301607
20360068
20628086
21988832
22820163

Gene Ontology  (GO ID)

Biological Process

GO:0030047  actin modification
GO:0051016  barbed-end actin filament capping
GO:0051301  cell division
GO:0007067  mitosis

Cellular Component

GO:0015629  actin cytoskeleton
GO:0005737  cytoplasm
GO:0005815  microtubule organizing center
GO:0030496  midbody
GO:0005634  nucleus

Molecular Function

GO:0051015  actin filament binding
GO:0017049  GTP-Rho binding
GO:0045159  myosin II binding
GO:0005543  phospholipid binding
GO:0031625  ubiquitin protein ligase binding