adrenergic, alpha-1A-, receptor

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Synonym

ADRA1C, Alpha-1C adrenergic receptor, Alpha 1A-adrenoceptor, ADRA1L1, adrenergic, alpha-1A-, receptor, Alpha-1A adrenergic receptor, Alpha 1A-adrenoreceptor, ALPHA1AAR, alpha-1A-, Alpha adrenergic receptor 1c, ADRA1A, alpha1A-AR

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.65 cerebellum:3.52 brain stem:3.67 corpus callosum/glia:3.58 pineal gland:- peripheral nerve:3.53 spine:3.58 retina:- eye:- artery/aorta:3.54 vein:3.71 lymphnode:3.62 peripheral blood:- spleen:3.60 thymus:3.38 bone marrow:3.67 adipose:3.67 bone:- skin:3.68
CAGE cerebrum:1.03 cerebellum:- brain stem:1.02 corpus callosum/glia:1.47 pineal gland:1.75 peripheral nerve:- spine:0.80 retina:- eye:- artery/aorta:0.47 vein:0.18 lymphnode:0.44 peripheral blood:- spleen:1.26 thymus:0 bone marrow:- adipose:0.71 bone:- skin:-
RNA-seq cerebrum:0.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.50 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.40 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:3.59 placenta:3.57 prostate:3.48 ovary:3.54 testis:3.49 heart:3.83 muscle:3.97 esophagus:3.55 stomach:3.70 intestine:3.77 colon:3.89 liver/hepato:4.16 lung:3.52 bladder:- kidney:3.79 pituitary:3.46 thyroid/parathyroid:3.39 adrenal gland:3.54 pancreas:3.82 breast:3.49 salivary:3.88
CAGE uterus:0.41 placenta:0 prostate:0.58 ovary:0.07 testis:0.16 heart:0.68 muscle:0.25 esophagus:0 stomach:- intestine:0.07 colon:0.18     liver/hepato:3.01    lung:0.21 bladder:0.09 kidney:0.21 pituitary:0.10 thyroid/parathyroid:0.12 adrenal gland:- pancreas:0 breast:0 salivary:1.95
RNA-seq uterus:- placenta:- prostate:0.24 ovary:0.20 testis:0.09 heart:0.87 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.13     liver/hepato:1.58        lung:0.55    bladder:- kidney:0.17 pituitary:- thyroid/parathyroid:0.39 adrenal gland:0.26 pancreas:- breast:1.50 salivary:-

Gene Ontology  (GO ID)

Biological Process

GO:0007202  activation of phospholipase C activity
GO:0007200  activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0007512  adult heart development
GO:0007568  aging
GO:0006915  apoptosis
GO:0060402  calcium ion transport into cytosol
GO:0016049  cell growth
GO:0007267  cell-cell signaling
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0060073  micturition
GO:0008285  negative regulation of cell proliferation
GO:0001985  negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure
GO:0035024  negative regulation of Rho protein signal transduction
GO:0032229  negative regulation of synaptic transmission, GABAergic
GO:0001994  norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
GO:0035265  organ growth
GO:0045760  positive regulation of action potential
GO:0060452  positive regulation of cardiac muscle contraction
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0001996  positive regulation of heart rate by epinephrine-norepinephrine
GO:0043410  positive regulation of MAPKKK cascade
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0045987  positive regulation of smooth muscle contraction
GO:0003084  positive regulation of systemic arterial blood pressure
GO:0001997  positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0045907  positive regulation of vasoconstriction
GO:0007243  protein kinase cascade
GO:0042493  response to drug
GO:0009725  response to hormone stimulus
GO:0006950  response to stress
GO:0007165  signal transduction
GO:0006939  smooth muscle contraction

Cellular Component

GO:0005887  integral to plasma membrane
GO:0031965  nuclear membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0030315  T-tubule
GO:0030018  Z disc

Molecular Function

GO:0004937  alpha1-adrenergic receptor activity
GO:0046982  protein heterodimerization activity