adrenergic, beta-3-, receptor

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Synonym

ADRB3R, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, B3AR, ADRB3, BETA3AR, Beta-3 adrenergic receptor, adrenergic, beta-3-, receptor

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:12.90 bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.45 cerebellum:4.44 brain stem:4.64 corpus callosum/glia:4.27 pineal gland:- peripheral nerve:4.12 spine:4.14 retina:- eye:- artery/aorta:4.27 vein:4.45 lymphnode:4.14 peripheral blood:- spleen:4.06 thymus:4.26 bone marrow:4.18 adipose:4.26 bone:- skin:4.52
CAGE cerebrum:0.17 cerebellum:- brain stem:0.03 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0.96 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.02 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:25.50 prostate:11.30 ovary:111.80 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.26 placenta:4.05 prostate:4.27 ovary:4.38 testis:4.15 heart:4.15 muscle:4.65 esophagus:4.42 stomach:4.24 intestine:4.44 colon:4.27 liver/hepato:4.33 lung:4.38 bladder:- kidney:4.24 pituitary:4.33 thyroid/parathyroid:4.12 adrenal gland:4.13 pancreas:4.59 breast:4.16 salivary:4.35
CAGE uterus:0.76 placenta:1.11 prostate:1.61 ovary:2.42 testis:0.19 heart:0.03 muscle:0 esophagus:1.01 stomach:- intestine:0.73 colon:0.69     liver/hepato:0    lung:0.10 bladder:2.25 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:1.81 ovary:3.11 testis:0.16 heart:0.02 muscle:0 esophagus:- stomach:- intestine:- colon:0.50     liver/hepato:0        lung:0    bladder:- kidney:0.07 pituitary:- thyroid/parathyroid:0 adrenal gland:0.02 pancreas:- breast:0.26 salivary:-

IDs

Refseq ID NM_000025
Gene ID 155
Unigene ID Hs.2549
Probe set ID 217303_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000188778
GTEx ID ENSG00000188778

Orthologous Gene

Mouse[2]  NM_013462
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1336117
1718744
2570461
7565630
7609625
7609752
7898940
8011597
8288218
8380813
8389293
8389717
8641219
8721782
9126344
9892244
10391210
10786926
10805511
10999801
11013230
11093283
11095426
11147800
11206402
11213599
11229427
11244458
11287026
11288809
11315829
11380082
11434877
11439286
11466580
11522702
11532330
11573151
11576322
11592045
11699048
11706779
11716317
11743056
11743057
11769635
11798745
11808891
11854867
11872697
11875710
11882399
11949887
11984699
12008746
12036966
12037740
12062855
12082592
12133431
12164325
12169859
12241539
12370850
12406043
12410955
12411100
12442007
12453902
12477932
12544508
12561621
12568179
12629568
12647276
12670949
12690078
12709137
12732844
12739018
12739037
12824951
12917707
12962933
14506613
14510956
14671190
14690019
14708035
14713387
14715679
14739355
14742851
14747257
15042014
15061987
15079793
15123695
15166301
15179018
15192823
15193960
15302798
15318095
15334374
15334382
15340101
15355441
15464701
15472194
15479221
15489334
15489932
15536594
15543217
15563584
15585565
15613846
15641247
15670186
15743038
15751274
15824464
15833937
15915764
15917856
15932670
15939803
15942638
15956122
15959859
16009000
16027735
16054001
16276029
16286518
16301818
16320158
16344560
16369102
16408483
16444766
16449022
16493638
16648810
16715838
16779985
16820065
17046546
17087055
17124363
17190106
17225053
17264845
17270896
17299381
17299491
17342473
17345787
17345789
17378367
17439327
17445027
17476189
17512307
17591269
17616777
17624182
17626108
17631141
17640319
17727676
17785925
17786291
17852419
17910280
17940985
17989355
17998022
17999941
18054709
18088254
18239290
18240029
18249022
18249219
18273796
18311486
18331634
18335327
18393130
18422027
18426866
18441513
18482921
18484422
18510051
18513389
18574485
18611262
18617734
18625943
18636124
18704193
18724972
18753860
18820136
18852493
18936436
18940396
18996102
18996293
19026982
19056576
19080138
19099777
19131662
19193342
19263529
19271249
19295193
19367093
19420105
19479237
19491387
19553224
19565482
19576569
19578796
19587357
19659999
19779464
19842096
19913121
20008926
20044737
20069060
20078877
20144152
20203292
20384434
20401689
20410100
20449541
20459474
20467565
20468064
20503258
20536507
20602615
20628086
20662153
20686326
20705341
20730725
20735409
20803423
20831043
20953633
21033077
21034552
21085551
21285172
21358132
21529759
21878665
21940308
21959333
21992420
22306453
22430195
22550477
22609474
22692629
22743651
22774401
22774474
22972489
23032405
23113754
23235150
23282015
23292548
23360304
23388888
23454374
23640967
23729572
23736006
23907236
23968135
24190960
24556804

Gene Ontology  (GO ID)

Biological Process

GO:0007190  activation of adenylate cyclase activity
GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007568  aging
GO:0050873  brown fat cell differentiation
GO:0005975  carbohydrate metabolic process
GO:0002032  desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0002024  diet induced thermogenesis
GO:0042755  eating behavior
GO:0006112  energy reserve metabolic process
GO:0007188  G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007187  G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0006091  generation of precursor metabolites and energy
GO:0031649  heat generation
GO:0040015  negative regulation of multicellular organism growth
GO:0043410  positive regulation of MAPKKK cascade
GO:0006898  receptor-mediated endocytosis
GO:0046677  response to antibiotic
GO:0009409  response to cold
GO:0002025  vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure

Cellular Component

GO:0005887  integral to plasma membrane
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0043235  receptor complex

Molecular Function

GO:0031699  beta-3 adrenergic receptor binding
GO:0004939  beta-adrenergic receptor activity
GO:0015052  beta3-adrenergic receptor activity
GO:0051379  epinephrine binding
GO:0051380  norepinephrine binding
GO:0005515  protein binding
GO:0042803  protein homodimerization activity