EPH receptor B4

Synonym

EphB4, Tyrosine-protein kinase receptor HTK, Ephrin type-B receptor 4 precursor, TYRO11, MYK1, Tyro11, EPH receptor B4, HTK, EPHB4

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:9.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:112.30

retina:-

eye:41.10

artery/aorta:89.90

vein:66.60

lymphnode:10.10

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:25.60

skin:43.20

GeneChip

cerebrum:7.06

cerebellum:7.25

brain stem:7.14

corpus callosum/glia:7.05

pineal gland:-

peripheral nerve:6.55

spine:6.66

retina:-

eye:-

artery/aorta:6.86

vein:7.29

lymphnode:7.05

peripheral blood:-

spleen:6.92

thymus:6.20

bone marrow:6.99

adipose:7.15

bone:-

skin:6.88

CAGE

cerebrum:0.78

cerebellum:-

brain stem:0.96

corpus callosum/glia:1.23

pineal gland:0.62

peripheral nerve:-

spine:1.00

retina:-

eye:-

artery/aorta:2.34

vein:2.29

lymphnode:2.30

peripheral blood:-

spleen:4.06

thymus:0.83

bone marrow:-

adipose:2.71

bone:-

skin:-

RNA-seq

cerebrum:0.94

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.47

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.01

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:80.10

prostate:11.30

ovary:74.50

testis:8.70

heart:63.90

muscle:-

esophagus:-

stomach:-

intestine:64.80

colon:50.90

liver/hepato:-

lung:34.20

bladder:-

kidney:83.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:35.60

breast:46.50

salivary:-

GeneChip

uterus:7.24

placenta:7.15

prostate:6.74

ovary:7.27

testis:6.64

heart:7.35

muscle:7.26

esophagus:7.06

stomach:7.08

intestine:7.09

colon:7.44

liver/hepato:7.48

lung:7.20

bladder:-

kidney:7.33

pituitary:6.93

thyroid/parathyroid:6.79

adrenal gland:7.43

pancreas:7.37

breast:7.07

salivary:7.32

CAGE

uterus:3.55

placenta:3.56

prostate:2.77

ovary:3.29

testis:2.62

heart:3.08

muscle:1.46

esophagus:2.54

stomach:-

intestine:1.99

colon:2.66

liver/hepato:3.43

lung:3.06

bladder:2.00

kidney:2.88

pituitary:1.02

thyroid/parathyroid:2.30

adrenal gland:-

pancreas:2.34

breast:3.12

salivary:2.46

RNA-seq

uterus:-

placenta:-

prostate:2.76

ovary:4.81

testis:3.45

heart:2.64

muscle:0.76

esophagus:-

stomach:-

intestine:-

colon:3.06

liver/hepato:3.86

lung:2.97

bladder:-

kidney:3.32

pituitary:-

thyroid/parathyroid:2.93

adrenal gland:4.38

pancreas:-

breast:3.54

salivary:-

IDs

Refseq ID	NM_004444
Gene ID	2050
Unigene ID	Hs.437008
Probe set ID	216680_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000196411
GTEx ID	ENSG00000196411

Orthologous Gene

Mouse[2]	NM_001159571, NM_010144
Rat[2]	NM_001159571, NM_010144

Chromosomal Region

7q22.1 [100,400,187 - 100,425,121]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0007155	cell adhesion
GO:0002042	cell migration involved in sprouting angiogenesis
GO:0048013	ephrin receptor signaling pathway
GO:0003007	heart morphogenesis
GO:0046777	protein amino acid autophosphorylation

Cellular Component

GO:0009986	cell surface
GO:0005887	integral to plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005003	ephrin receptor activity
GO:0005515	protein binding
GO:0004714	transmembrane receptor protein tyrosine kinase activity

IPR001090	Ephrin receptor, ligand binding
IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR008979	Galactose-binding domain-like
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001660	Sterile alpha motif
IPR010993	Sterile alpha motif homology
IPR013761	Sterile alpha motif-type
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR016257	Tyrosine-protein kinase, ephrin receptor
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

EPH receptor B4

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function