UTP20, small subunit (SSU) processome component, homolog (yeast)

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Synonym

UTP20, Small subunit processome component 20 homolog, DRIM, Novel nucleolar protein 73, NNP73, Down-regulated in metastasis protein, Protein Key-1A6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:30.70 spine:112.30 retina:- eye:11.80 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:18.90 thymus:12.90 bone marrow:- adipose:- bone:25.60 skin:14.40
GeneChip cerebrum:5.32 cerebellum:5.46 brain stem:5.39 corpus callosum/glia:5.49 pineal gland:- peripheral nerve:5.79 spine:5.42 retina:- eye:- artery/aorta:5.61 vein:5.67 lymphnode:5.72 peripheral blood:- spleen:5.79 thymus:5.39 bone marrow:5.61 adipose:5.71 bone:- skin:5.65
CAGE cerebrum:2.54 cerebellum:- brain stem:2.62 corpus callosum/glia:2.90 pineal gland:2.75 peripheral nerve:- spine:2.59 retina:- eye:- artery/aorta:2.62 vein:2.70 lymphnode:3.09 peripheral blood:- spleen:2.83 thymus:2.72 bone marrow:- adipose:3.10 bone:- skin:-
RNA-seq cerebrum:0.99 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.40 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.61 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:18.20 prostate:33.80 ovary:- testis:13 heart:- muscle:20.10 esophagus:- stomach:148.70 intestine:- colon:25.40     liver/hepato:21.10        lung:29.30    bladder:- kidney:- pituitary:- thyroid/parathyroid:163.70 adrenal gland:50.80 pancreas:71.10 breast:83.60 salivary:-
GeneChip uterus:5.67 placenta:5.20 prostate:5.53 ovary:5.71 testis:5.80 heart:5.77 muscle:5.81 esophagus:5.66 stomach:5.56 intestine:5.40 colon:5.39 liver/hepato:5.68 lung:5.44 bladder:- kidney:5.56 pituitary:5.58 thyroid/parathyroid:5.44 adrenal gland:6.04 pancreas:5.57 breast:5.88 salivary:5.77
CAGE uterus:2.74 placenta:2.48 prostate:2.65 ovary:3.18 testis:2.99 heart:2.71 muscle:2.67 esophagus:2.59 stomach:- intestine:2.04 colon:2.66     liver/hepato:2.73    lung:2.75 bladder:2.45 kidney:2.46 pituitary:2.56 thyroid/parathyroid:2.45 adrenal gland:- pancreas:2.98 breast:3.12 salivary:2.63
RNA-seq uterus:- placenta:- prostate:1.78 ovary:2.39 testis:2.23 heart:1.35 muscle:1.58 esophagus:- stomach:- intestine:- colon:1.52     liver/hepato:1.24        lung:0.88    bladder:- kidney:1.65 pituitary:- thyroid/parathyroid:1.83 adrenal gland:2.29 pancreas:- breast:1.55 salivary:-

Gene Information

IDs

Refseq ID NM_014503
Gene ID 27340
Unigene ID Hs.295732
Probe set ID 209725_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000120800
GTEx ID ENSG00000120800

Orthologous Gene

Mouse[1]  NM_175158
Rat [0]  

Chromosomal Region

12q23.2  [101,673,887  -  101,780,394]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7566098
9673349
11790298
12150911
12429849
12837249
14503924
15302935
15590835
15635413
15656982
16053918
16458307
16565220
17498821
17652137
17903303
19471022
19596686
20197096
21139048
21151873
21890473
21963094
22108332
22586326
22939629
24250222
24457600
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0000480  endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000447  endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472  endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0008285  negative regulation of cell proliferation
GO:0006364  rRNA processing

Cellular Component

GO:0030686  90S preribosome
GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0030688  preribosome, small subunit precursor
GO:0032040  small-subunit processome

Molecular Function

GO:0005515  protein binding