glycine receptor, alpha 1

Synonym

MGC138878, STHE, Glycine receptor 48 kDa subunit, Glycine receptor subunit alpha-1 precursor, Glycine receptor strychnine-binding subunit, MGC138879, GLRA1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:25.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:10.10

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:40.30

bone:-

skin:-

GeneChip

cerebrum:3.58

cerebellum:3.78

brain stem:3.64

corpus callosum/glia:3.52

pineal gland:-

peripheral nerve:3.55

spine:3.68

retina:-

eye:-

artery/aorta:3.58

vein:3.93

lymphnode:3.52

peripheral blood:-

spleen:3.43

thymus:3.31

bone marrow:3.77

adipose:3.62

bone:-

skin:3.57

CAGE

cerebrum:0.64

cerebellum:-

brain stem:1.25

corpus callosum/glia:0.34

pineal gland:0

peripheral nerve:-

spine:2.50

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.05

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:8.50

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.42

placenta:3.14

prostate:3.17

ovary:3.41

testis:3.32

heart:3.65

muscle:3.72

esophagus:3.45

stomach:3.61

intestine:3.53

colon:3.80

liver/hepato:3.45

lung:3.59

bladder:-

kidney:3.44

pituitary:3.70

thyroid/parathyroid:3.47

adrenal gland:3.46

pancreas:3.73

breast:3.40

salivary:3.54

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0

heart:0.09

muscle:0

esophagus:0

stomach:-

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:0

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:1.21

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0

ovary:0.01

testis:0

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0

adrenal gland:0

pancreas:-

breast:0.01

salivary:-

IDs

Refseq ID	NM_000171
Gene ID	2741
Unigene ID	Hs.121490
Probe set ID	207972_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000145888
GTEx ID	ENSG00000145888

Orthologous Gene

Mouse[1]	NM_020492
Rat [0]

Chromosomal Region

5q33.1 [151,202,074 - 151,304,403]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006028	Gamma-aminobutyric acid A receptor
IPR008128	Glycine receptor alpha1
IPR006201	Neurotransmitter-gated ion-channel

Gene Ontology (GO ID)

Biological Process

GO:0007340	acrosome reaction
GO:0007628	adult walking behavior
GO:0006821	chloride transport
GO:0034220	ion transmembrane transport
GO:0006811	ion transport
GO:0006936	muscle contraction
GO:0051970	negative regulation of transmission of nerve impulse
GO:0050884	neuromuscular process controlling posture
GO:0007218	neuropeptide signaling pathway
GO:0051291	protein heterooligomerization
GO:0051260	protein homooligomerization
GO:0001508	regulation of action potential
GO:0060080	regulation of inhibitory postsynaptic membrane potential
GO:0042391	regulation of membrane potential
GO:0002087	regulation of respiratory gaseous exchange by neurological system process
GO:0060013	righting reflex
GO:0001964	startle response
GO:0060012	synaptic transmission, glycinergic
GO:0055085	transmembrane transport
GO:0007601	visual perception

Cellular Component

GO:0030054	cell junction
GO:0034707	chloride channel complex
GO:0005783	endoplasmic reticulum
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane

Molecular Function

GO:0016934	extracellular-glycine-gated chloride channel activity
GO:0016594	glycine binding
GO:0005515	protein binding
GO:0030977	taurine binding
GO:0022824	transmitter-gated ion channel activity

glycine receptor, alpha 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function