ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1

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Synonym

Vacuolar ATP synthase subunit B, kidney isoform, 56/58kD, Endomembrane proton pump 58 kDa subunit, beta polypeptide, VATB, ATP6V1B1, VPP3, ATP6B1, MGC32642, Vma2, V1 subunit B, RTA1B, lysosomal 56/58kDa, Vacuolar proton pump B isoform 1, V-ATPase B1 subunit, VMA2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:35.30 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.88 cerebellum:5.04 brain stem:4.94 corpus callosum/glia:4.79 pineal gland:- peripheral nerve:4.67 spine:4.69 retina:- eye:- artery/aorta:5.05 vein:4.96 lymphnode:4.83 peripheral blood:- spleen:4.52 thymus:4.71 bone marrow:4.88 adipose:5.07 bone:- skin:5.64
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.18 vein:0 lymphnode:0.55 peripheral blood:- spleen:0 thymus:0.18 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.30 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:116.60 prostate:- ovary:37.30 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:19.60    bladder:- kidney:343.10 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:92.90 salivary:328.40
GeneChip uterus:4.87 placenta:5.64 prostate:4.77 ovary:5.12 testis:4.80 heart:4.88 muscle:4.98 esophagus:4.93 stomach:4.69 intestine:4.98 colon:4.92 liver/hepato:4.75 lung:4.93 bladder:- kidney:6.92 pituitary:5.40 thyroid/parathyroid:4.72 adrenal gland:4.64 pancreas:5.42 breast:5.25 salivary:7
CAGE uterus:1.15 placenta:4.03 prostate:0.62 ovary:1.56 testis:0.19 heart:0 muscle:0 esophagus:0.52 stomach:- intestine:0 colon:0     liver/hepato:0    lung:1.49 bladder:0 kidney:4.30 pituitary:1.98 thyroid/parathyroid:0 adrenal gland:- pancreas:0.94 breast:1.16 salivary:5.52
RNA-seq uterus:- placenta:- prostate:0.56 ovary:1.07 testis:0.07 heart:0.02 muscle:0.05 esophagus:- stomach:- intestine:- colon:0.10     liver/hepato:0        lung:1.56    bladder:- kidney:4.15 pituitary:- thyroid/parathyroid:0.05 adrenal gland:0.21 pancreas:- breast:1.95 salivary:-

Gene Information

IDs

Refseq ID NM_001692
Gene ID 525
Unigene ID Hs.64173
Probe set ID 205473_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000116039
GTEx ID ENSG00000116039

Orthologous Gene

Mouse[1]  NM_134157
Rat [0]  

Chromosomal Region

2p13.3  [71,163,012  -  71,192,555]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2527371
2874839
7945239
8125298
8597961
8849440
8889548
9210392
9442887
9916796
10221984
10224039
10340843
10440860
10748165
10915794
11836511
12414817
12477932
12500243
12579397
12651853
12788495
14580332
14585495
14597263
14702039
16344560
16433694
16928804
17216496
17662945
18180394
19008710
19056867
19478356
19639346
19913121
20233014
20622307
20628086
20805693
21674799
22509993
22939629
23455924
23729491
23923981
24252324
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0015991  ATP hydrolysis coupled proton transport
GO:0046034  ATP metabolic process
GO:0055074  calcium ion homeostasis
GO:0006879  cellular iron ion homeostasis
GO:0007588  excretion
GO:0042472  inner ear morphogenesis
GO:0008286  insulin receptor signaling pathway
GO:0051701  interaction with host
GO:0001503  ossification
GO:0045851  pH reduction
GO:0015992  proton transport
GO:0006885  regulation of pH
GO:0007605  sensory perception of sound
GO:0033572  transferrin transport
GO:0055085  transmembrane transport

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0012505  endomembrane system
GO:0016328  lateral plasma membrane
GO:0005902  microvillus
GO:0033180  proton-transporting V-type ATPase, V1 domain
GO:0016471  vacuolar proton-transporting V-type ATPase complex

Molecular Function

GO:0005524  ATP binding
GO:0015078  hydrogen ion transmembrane transporter activity
GO:0016820  hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0032403  protein complex binding