Fanconi anemia, complementation group L

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Synonym

POG, PHD finger protein 9, Ubiquitin ligase protein FANCL, Fanconi anemia-associated polypeptide of 43 kDa, PHF9, FANCL, Fanconi anemia, complementation group L, FLJ10335, Fanconi anemia group L protein, FAAP43

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:67.60 cerebellum:88.20 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:35.30 artery/aorta:- vein:66.60 lymphnode:182 peripheral blood:- spleen:18.90 thymus:- bone marrow:- adipose:- bone:12.80 skin:38.40
GeneChip cerebrum:6.86 cerebellum:5.31 brain stem:7.68 corpus callosum/glia:7.61 pineal gland:- peripheral nerve:6.03 spine:7.18 retina:- eye:- artery/aorta:5.85 vein:4.99 lymphnode:6.69 peripheral blood:- spleen:6.92 thymus:7.32 bone marrow:5.96 adipose:5.57 bone:- skin:5.64
CAGE cerebrum:3.54 cerebellum:- brain stem:4.18 corpus callosum/glia:4.22 pineal gland:3.78 peripheral nerve:- spine:3.74 retina:- eye:- artery/aorta:2.81 vein:2.70 lymphnode:2.73 peripheral blood:- spleen:2.90 thymus:2.85 bone marrow:- adipose:2.74 bone:- skin:-
RNA-seq cerebrum:2.08 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.45 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.85 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:14.60 prostate:56.30 ovary:74.50 testis:95.20 heart:51.10 muscle:60.30 esophagus:- stomach:21.20 intestine:64.80 colon:84.80     liver/hepato:31.70        lung:44    bladder:251.20 kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:17.80 breast:130.10 salivary:-
GeneChip uterus:7.37 placenta:5.76 prostate:7.40 ovary:7.01 testis:7.16 heart:5.68 muscle:5.65 esophagus:5.88 stomach:6.34 intestine:6.17 colon:5.25 liver/hepato:6.91 lung:6.19 bladder:- kidney:5.42 pituitary:8.18 thyroid/parathyroid:6.89 adrenal gland:8.22 pancreas:5.23 breast:6.32 salivary:6.81
CAGE uterus:3.56 placenta:2.54 prostate:3.09 ovary:2.96 testis:3.46 heart:2.70 muscle:2.21 esophagus:2.39 stomach:- intestine:3.11 colon:2.55     liver/hepato:2.54    lung:2.71 bladder:2.62 kidney:2.29 pituitary:4.76 thyroid/parathyroid:3.22 adrenal gland:- pancreas:2.90 breast:2.19 salivary:3.56
RNA-seq uterus:- placenta:- prostate:2.98 ovary:2.76 testis:3.52 heart:1.19 muscle:0.87 esophagus:- stomach:- intestine:- colon:1.69     liver/hepato:1.50        lung:0.08    bladder:- kidney:2.64 pituitary:- thyroid/parathyroid:2.14 adrenal gland:1.99 pancreas:- breast:2.47 salivary:-

Gene Information

IDs

Refseq ID NM_018062
Gene ID 55120
Unigene ID Hs.631890
Probe set ID 218397_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000115392
GTEx ID ENSG00000115392

Orthologous Gene

Mouse[1]  NM_025923
Rat [0]  

Chromosomal Region

2p16.1  [58,386,378  -  58,468,507]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
12417526
12477932
12574169
12606378
12724401
12973351
14702039
15489334
15502827
15761153
15815621
16116422
16344560
16474167
16720839
16916645
17106252
17289582
17396147
17938197
18174376
18270339
18285517
18550849
18607065
19111657
19589784
19690177
19737859
20301575
20301753
20347428
20347429
20407210
20935630
20937699
21229326
21297076
21543111
21697891
21775430
21906983
21963094
21975120
22287633
22653977
22705371
22797925
22828653
23563607
23783032
24250222
24389026
24623813

Gene Ontology  (GO ID)

Biological Process

GO:0006281  DNA repair
GO:0007276  gamete generation
GO:0006513  protein monoubiquitination
GO:0042127  regulation of cell proliferation
GO:0006974  response to DNA damage stimulus

Cellular Component

GO:0005737  cytoplasm
GO:0043240  Fanconi anaemia nuclear complex
GO:0005635  nuclear envelope
GO:0005654  nucleoplasm

Molecular Function

GO:0031625  ubiquitin protein ligase binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding