protein kinase N1

Synonym

protein kinase N1, PKN, Protein kinase C-like 1, protein kinase C-like 1, PRKCL1, Protein-kinase C-related kinase 1, DBK, PKN1, PAK1, PRK1, MGC46204, Serine/threonine-protein kinase N1, Serine-threonine protein kinase N, Protein kinase PKN-alpha, Protein kinase C-like PKN

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:67.60

cerebellum:12.60

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:122.70

spine:112.30

retina:-

eye:146.90

artery/aorta:30

vein:199.90

lymphnode:171.90

peripheral blood:164

spleen:94.50

thymus:206.10

bone marrow:19.70

adipose:-

bone:76.80

skin:38.40

GeneChip

cerebrum:6.02

cerebellum:6.25

brain stem:6.08

corpus callosum/glia:6.23

pineal gland:-

peripheral nerve:6.13

spine:6.08

retina:-

eye:-

artery/aorta:6.79

vein:6.46

lymphnode:6.89

peripheral blood:-

spleen:7.21

thymus:6.31

bone marrow:6.61

adipose:6.61

bone:-

skin:5.94

CAGE

cerebrum:2.90

cerebellum:-

brain stem:2.93

corpus callosum/glia:3.24

pineal gland:2.59

peripheral nerve:-

spine:2.62

retina:-

eye:-

artery/aorta:3.27

vein:3.54

lymphnode:3.63

peripheral blood:-

spleen:3.82

thymus:3.69

bone marrow:-

adipose:3.28

bone:-

skin:-

RNA-seq

cerebrum:0.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.13

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.78

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:47.40

prostate:112.60

ovary:149.10

testis:73.50

heart:51.10

muscle:40.20

esophagus:-

stomach:42.50

intestine:-

colon:76.30

liver/hepato:10.60

lung:29.30

bladder:-

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:83.60

salivary:328.40

GeneChip

uterus:6.25

placenta:5.84

prostate:6.06

ovary:6.13

testis:6.80

heart:6.27

muscle:6.22

esophagus:5.89

stomach:6.33

intestine:6.08

colon:6.07

liver/hepato:6.14

lung:6.57

bladder:-

kidney:6.15

pituitary:6.47

thyroid/parathyroid:6.35

adrenal gland:6.35

pancreas:6.21

breast:6.25

salivary:6.30

CAGE

uterus:3.07

placenta:3.17

prostate:3.35

ovary:3.27

testis:3.46

heart:3.41

muscle:3.31

esophagus:3.00

stomach:-

intestine:2.51

colon:3.01

liver/hepato:2.86

lung:3.52

bladder:3.21

kidney:2.94

pituitary:2.41

thyroid/parathyroid:2.99

adrenal gland:-

pancreas:3.45

breast:3.52

salivary:2.60

RNA-seq

uterus:-

placenta:-

prostate:3.18

ovary:1.36

testis:1.44

heart:2.92

muscle:2.98

esophagus:-

stomach:-

intestine:-

colon:1.57

liver/hepato:1.24

lung:3.38

bladder:-

kidney:1.74

pituitary:-

thyroid/parathyroid:1.85

adrenal gland:1.90

pancreas:-

breast:1.55

salivary:-

IDs

Refseq ID	NM_002741
Gene ID	5585
Unigene ID	Hs.466044
Probe set ID	202161_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000123143
GTEx ID	ENSG00000123143

Orthologous Gene

Mouse[1]	NM_001199593, NM_177262
Rat [0]

Chromosomal Region

19p13.12 [14,544,169 - 14,582,678]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000961	AGC-kinase, C-terminal
IPR011072	HR1 rho-binding repeat
IPR000861	HR1-like rho-binding repeat
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0007257	activation of JUN kinase activity
GO:0010631	epithelial cell migration
GO:0006972	hyperosmotic response
GO:0006468	protein amino acid phosphorylation
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0007165	signal transduction
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0032154	cleavage furrow
GO:0005737	cytoplasm
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0005768	endosome
GO:0030496	midbody
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0050681	androgen receptor binding
GO:0005524	ATP binding
GO:0003682	chromatin binding
GO:0017049	GTP-Rho binding
GO:0042393	histone binding
GO:0042826	histone deacetylase binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004697	protein kinase C activity
GO:0005080	protein kinase C binding
GO:0004674	protein serine/threonine kinase activity
GO:0048365	Rac GTPase binding

protein kinase N1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function