mitogen-activated protein kinase 13

Synonym

MGC99536, Mitogen-activated protein kinase 13, PRKM13, Mitogen-activated protein kinase p38 delta, MAP kinase p38 delta, SAPK4, MAPK13, Stress-activated protein kinase 4, mitogen-activated protein kinase 13, p38delta

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:9.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:35.30

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:18.20

spleen:18.90

thymus:-

bone marrow:-

adipose:-

bone:-

skin:33.60

GeneChip

cerebrum:5.19

cerebellum:4.89

brain stem:4.97

corpus callosum/glia:4.98

pineal gland:-

peripheral nerve:5.12

spine:5.04

retina:-

eye:-

artery/aorta:5.51

vein:5.25

lymphnode:6.23

peripheral blood:-

spleen:5.50

thymus:5.74

bone marrow:5.54

adipose:5.72

bone:-

skin:6.93

CAGE

cerebrum:1.21

cerebellum:-

brain stem:0.77

corpus callosum/glia:0.34

pineal gland:1.27

peripheral nerve:-

spine:0.58

retina:-

eye:-

artery/aorta:1.10

vein:1.73

lymphnode:2.78

peripheral blood:-

spleen:1.09

thymus:1.60

bone marrow:-

adipose:2.17

bone:-

skin:-

RNA-seq

cerebrum:0.92

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.40

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:25.50

prostate:33.80

ovary:-

testis:34.60

heart:-

muscle:-

esophagus:-

stomach:21.20

intestine:32.40

colon:42.40

liver/hepato:-

lung:44

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:62.20

breast:27.90

salivary:-

GeneChip

uterus:5.51

placenta:6.58

prostate:6.05

ovary:5.14

testis:7.47

heart:5.40

muscle:5.14

esophagus:7.90

stomach:6.37

intestine:6.31

colon:6.91

liver/hepato:5.29

lung:5.99

bladder:-

kidney:5.86

pituitary:6.80

thyroid/parathyroid:6.24

adrenal gland:7.06

pancreas:6.87

breast:6.60

salivary:7.48

CAGE

uterus:1.51

placenta:2.45

prostate:2.15

ovary:1.59

testis:3.29

heart:0.53

muscle:0.21

esophagus:3.33

stomach:-

intestine:3.67

colon:3.21

liver/hepato:0.71

lung:2.58

bladder:1.56

kidney:1.89

pituitary:2.39

thyroid/parathyroid:2.64

adrenal gland:-

pancreas:3.23

breast:1.92

salivary:2.90

RNA-seq

uterus:-

placenta:-

prostate:3.11

ovary:2.18

testis:4.33

heart:0.39

muscle:0.06

esophagus:-

stomach:-

intestine:-

colon:2.06

liver/hepato:0.88

lung:3.25

bladder:-

kidney:2.86

pituitary:-

thyroid/parathyroid:3.55

adrenal gland:3.34

pancreas:-

breast:1.73

salivary:-

IDs

Refseq ID	NM_002754
Gene ID	5603
Unigene ID	Hs.178695
Probe set ID	210058_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000156711
GTEx ID	ENSG00000156711

Orthologous Gene

Mouse[1]	NM_011950
Rat[1]	NM_019231

Chromosomal Region

6p21.31 [36,095,586 - 36,107,842]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR008351	JNK MAP kinase
IPR008352	MAP kinase, p38
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

GO:0007049	cell cycle
GO:0000165	MAPKKK cascade
GO:0048011	nerve growth factor receptor signaling pathway
GO:0018105	peptidyl-serine phosphorylation
GO:0050729	positive regulation of inflammatory response
GO:0032755	positive regulation of interleukin-6 production
GO:0007243	protein kinase cascade
GO:0007265	Ras protein signal transduction
GO:0006355	regulation of transcription, DNA-dependent
GO:0006970	response to osmotic stress
GO:0006950	response to stress
GO:0006351	transcription, DNA-dependent

GO:0005524	ATP binding
GO:0004707	MAP kinase activity
GO:0005515	protein binding
GO:0004674	protein serine/threonine kinase activity

mitogen-activated protein kinase 13

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function