peroxisomal membrane protein 3, 35kDa

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Synonym

PXMP3, PAF1, Peroxin-2, PMP35, PEX2, Peroxisomal membrane protein 3, PAF-1, RNF72, PMP3, 35 kDa peroxisomal membrane protein, Peroxisome assembly factor 1, RING finger protein 72

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:24
GeneChip cerebrum:5.58 cerebellum:5.14 brain stem:5.91 corpus callosum/glia:5.91 pineal gland:- peripheral nerve:5.82 spine:6.21 retina:- eye:- artery/aorta:5.42 vein:5.20 lymphnode:5.68 peripheral blood:- spleen:5.84 thymus:7.01 bone marrow:5.27 adipose:6.06 bone:- skin:5.68
CAGE cerebrum:3.42 cerebellum:- brain stem:3.57 corpus callosum/glia:3.52 pineal gland:3.60 peripheral nerve:- spine:3.99 retina:- eye:- artery/aorta:3.01 vein:3.25 lymphnode:3.53 peripheral blood:- spleen:3.47 thymus:3.62 bone marrow:- adipose:3.00 bone:- skin:-
RNA-seq cerebrum:1.54 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:18.20 prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:9.80    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.50 placenta:5.46 prostate:7.22 ovary:6.36 testis:5.74 heart:5.62 muscle:6.81 esophagus:5.68 stomach:5.89 intestine:6.22 colon:5.83 liver/hepato:5.53 lung:5.48 bladder:- kidney:6.10 pituitary:5.88 thyroid/parathyroid:6.28 adrenal gland:5.65 pancreas:6.07 breast:5.85 salivary:6.41
CAGE uterus:3.57 placenta:3.12 prostate:3.48 ovary:3.22 testis:3.14 heart:3.22 muscle:3.58 esophagus:3.33 stomach:- intestine:3.61 colon:3.31     liver/hepato:3.33    lung:3.32 bladder:3.55 kidney:3.71 pituitary:3.87 thyroid/parathyroid:3.79 adrenal gland:- pancreas:3.42 breast:2.99 salivary:3.87
RNA-seq uterus:- placenta:- prostate:1.38 ovary:0.98 testis:0.73 heart:1.71 muscle:1.31 esophagus:- stomach:- intestine:- colon:1.38     liver/hepato:0.00        lung:0.48    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.96 adrenal gland:0.04 pancreas:- breast:0.52 salivary:-

Gene Information

IDs

Refseq ID NM_001079867
Gene ID 5828
Unigene ID Hs.437966
Probe set ID 210296_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164751
GTEx ID ENSG00000164751

Orthologous Gene

Mouse[7]  NM_001163301, NM_001163302, NM_001163303, NM_001163304, NM_001163305, NM_001163306, NM_008994
Rat [0]  

Chromosomal Region

8q21.11  [77,892,494  -  77,913,280]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1426230
1546315
1750930
2454948
7600573
7681622
8020947
8858157
9452066
9765053
10528859
10837480
10891359
11590176
12477932
12751901
15342556
15489334
15542397
16169070
16344560
18391951
18987311
19946888
20301621
20379614
20546612
20881960
21102462
21392394
21525035
21658281
21832049
21903356
22002062
24501781

Gene Ontology  (GO ID)

Biological Process

GO:0006699  bile acid biosynthetic process
GO:0042632  cholesterol homeostasis
GO:0006635  fatty acid beta-oxidation
GO:0050680  negative regulation of epithelial cell proliferation
GO:0048147  negative regulation of fibroblast proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0001764  neuron migration
GO:0007031  peroxisome organization
GO:0031648  protein destabilization
GO:0016558  protein import into peroxisome matrix
GO:0045540  regulation of cholesterol biosynthetic process
GO:0000038  very-long-chain fatty acid metabolic process

Cellular Component

GO:0016593  Cdc73/Paf1 complex
GO:0005779  integral to peroxisomal membrane
GO:0005778  peroxisomal membrane

Molecular Function

GO:0005515  protein binding
GO:0008270  zinc ion binding