Rab geranylgeranyltransferase, alpha subunit

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Synonym

Geranylgeranyl transferase type II alpha subunit, Rab geranylgeranyltransferase, alpha subunit, RABGGTA, Rab GG transferase alpha, Rab GGTase alpha, Rab geranyl-geranyltransferase alpha subunit, Rab geranylgeranyltransferase alpha subunit, Geranylgeranyl transferase type-2 alpha subunit

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:80.60 cerebellum:151.10 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:58.80 artery/aorta:- vein:- lymphnode:91 peripheral blood:200.40 spleen:264.70 thymus:128.80 bone marrow:19.70 adipose:161.30 bone:89.60 skin:76.80
GeneChip cerebrum:6.02 cerebellum:5.94 brain stem:6.10 corpus callosum/glia:5.71 pineal gland:- peripheral nerve:6.46 spine:5.78 retina:- eye:- artery/aorta:6.21 vein:5.88 lymphnode:6.36 peripheral blood:- spleen:6.09 thymus:5.86 bone marrow:6.11 adipose:6.19 bone:- skin:6.55
CAGE cerebrum:2.63 cerebellum:- brain stem:2.71 corpus callosum/glia:2.67 pineal gland:2.45 peripheral nerve:- spine:2.34 retina:- eye:- artery/aorta:2.28 vein:2.51 lymphnode:3.05 peripheral blood:- spleen:2.68 thymus:2.28 bone marrow:- adipose:2.35 bone:- skin:-
RNA-seq cerebrum:1.25 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.60 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.89 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:98.40 prostate:78.90 ovary:37.30 testis:77.90 heart:38.30 muscle:20.10 esophagus:342.80 stomach:21.20 intestine:129.60 colon:8.50     liver/hepato:21.10        lung:44    bladder:125.60 kidney:72.80 pituitary:232 thyroid/parathyroid:- adrenal gland:355.50 pancreas:26.70 breast:9.30 salivary:-
GeneChip uterus:5.82 placenta:6.01 prostate:6.16 ovary:5.97 testis:6.44 heart:5.73 muscle:6.13 esophagus:7.24 stomach:5.75 intestine:5.97 colon:5.93 liver/hepato:5.79 lung:6.31 bladder:- kidney:6.03 pituitary:6.30 thyroid/parathyroid:6.24 adrenal gland:6.06 pancreas:5.77 breast:6.09 salivary:6.02
CAGE uterus:2.47 placenta:2.95 prostate:2.43 ovary:2.19 testis:2.85 heart:2.40 muscle:2.42 esophagus:3.31 stomach:- intestine:2.90 colon:2.72     liver/hepato:2.94    lung:2.87 bladder:2.03 kidney:2.88 pituitary:2.74 thyroid/parathyroid:2.49 adrenal gland:- pancreas:2.54 breast:2.34 salivary:2.35
RNA-seq uterus:- placenta:- prostate:1.16 ovary:1.66 testis:2.12 heart:0.89 muscle:0.75 esophagus:- stomach:- intestine:- colon:0.99     liver/hepato:0.44        lung:1.02    bladder:- kidney:1.26 pituitary:- thyroid/parathyroid:1.57 adrenal gland:1.21 pancreas:- breast:1.64 salivary:-

Gene Information

IDs

Refseq ID NM_004581
Gene ID 5875
Unigene ID Hs.377992
Probe set ID 203573_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100949
GTEx ID ENSG00000100949

Orthologous Gene

Mouse[1]  NM_019519
Rat[1]  NM_031654

Chromosomal Region

14q12  [24,734,746  -  24,740,803]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2018975
7991565
8380507
8505342
8954794
9196026
12071695
12107412
12477932
12535645
12620235
15188402
15489334
16344560
20403997
21890473
21906983
21963094
22863883
22939629
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0018344  protein geranylgeranylation
GO:0006464  protein modification process
GO:0007601  visual perception

Molecular Function

GO:0004663  Rab geranylgeranyltransferase activity
GO:0008270  zinc ion binding