ubiquitin specific peptidase 46

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Synonym

Ubiquitin carboxyl-terminal hydrolase 46, FLJ12552, ubiquitin specific protease 46, Ubiquitin-specific-processing protease 46, Ubiquitin thioesterase 46, Deubiquitinating enzyme 46, USP46, ubiquitin specific peptidase 46

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:4.70 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.06 cerebellum:6.86 brain stem:6.95 corpus callosum/glia:6.77 pineal gland:- peripheral nerve:7.01 spine:7.28 retina:- eye:- artery/aorta:5 vein:4.28 lymphnode:4.06 peripheral blood:- spleen:4.21 thymus:4.50 bone marrow:3.71 adipose:4.36 bone:- skin:4.27
CAGE cerebrum:4.03 cerebellum:- brain stem:3.64 corpus callosum/glia:3.82 pineal gland:3.45 peripheral nerve:- spine:3.87 retina:- eye:- artery/aorta:2.94 vein:2.51 lymphnode:2.40 peripheral blood:- spleen:2.25 thymus:1.83 bone marrow:- adipose:2.39 bone:- skin:-
RNA-seq cerebrum:0.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:7.30 prostate:- ovary:- testis:8.70 heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:14.70    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.23 placenta:6.46 prostate:5.62 ovary:5.31 testis:4.73 heart:5.81 muscle:6.01 esophagus:5.27 stomach:4.74 intestine:4.82 colon:4.44 liver/hepato:4.01 lung:4.07 bladder:- kidney:5.34 pituitary:4.87 thyroid/parathyroid:5.28 adrenal gland:5.22 pancreas:4.68 breast:4.37 salivary:5.09
CAGE uterus:2.85 placenta:3.52 prostate:2.50 ovary:2.81 testis:3.07 heart:3.38 muscle:2.73 esophagus:2.80 stomach:- intestine:2.34 colon:2.36     liver/hepato:1.90    lung:2.30 bladder:2.50 kidney:3.00 pituitary:2.71 thyroid/parathyroid:2.76 adrenal gland:- pancreas:2.76 breast:2.59 salivary:2.88
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:1.06 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001134223
Gene ID 64854
Unigene ID Hs.7966
Probe set ID 203870_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000109189
GTEx ID ENSG00000109189

Orthologous Gene

Mouse[1]  NM_177561
Rat [0]  

Chromosomal Region

4q12  [53,460,340  -  53,525,502]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8619474
9110174
12477932
12838346
14702039
14715245
15342556
15489334
19075014
19260141
19615732
20111060
20147737
21139048
21183687
21663972
22043315
22118674
22391563

Gene Ontology  (GO ID)

Biological Process

GO:0007610  behavior
GO:0001662  behavioral fear response
GO:0016579  protein deubiquitination
GO:0032228  regulation of synaptic transmission, GABAergic
GO:0006511  ubiquitin-dependent protein catabolic process

Molecular Function

GO:0005515  protein binding
GO:0004221  ubiquitin thiolesterase activity
GO:0004843  ubiquitin-specific protease activity