solute carrier family 19 (folate transporter), member 1

Synonym

IFC1, SLC19A1, RFC1, REFC, FLOT1, RFC, Intestinal folate carrier, Solute carrier family 19 member 1, Placental folate transporter, IFC-1, CHMD, Reduced folate carrier protein, Folate transporter 1, FOLT

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:40.30

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:296.70

peripheral nerve:30.70

spine:-

retina:-

eye:52.90

artery/aorta:60

vein:66.60

lymphnode:101.10

peripheral blood:18.20

spleen:18.90

thymus:77.30

bone marrow:59

adipose:80.70

bone:38.40

skin:19.20

GeneChip

cerebrum:5.74

cerebellum:5.79

brain stem:5.68

corpus callosum/glia:5.63

pineal gland:-

peripheral nerve:5.28

spine:5.42

retina:-

eye:-

artery/aorta:5.72

vein:5.56

lymphnode:5.69

peripheral blood:-

spleen:5.93

thymus:5.52

bone marrow:6.36

adipose:5.77

bone:-

skin:5.39

CAGE

cerebrum:1.96

cerebellum:-

brain stem:1.77

corpus callosum/glia:2.08

pineal gland:2.06

peripheral nerve:-

spine:1.92

retina:-

eye:-

artery/aorta:1.43

vein:2.16

lymphnode:2.27

peripheral blood:-

spleen:2.62

thymus:2.44

bone marrow:-

adipose:2.15

bone:-

skin:-

RNA-seq

cerebrum:0.52

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.67

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.94

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:54.60

prostate:56.30

ovary:-

testis:-

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:17

liver/hepato:-

lung:24.40

bladder:-

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:27.90

salivary:-

GeneChip

uterus:5.37

placenta:7.41

prostate:5.61

ovary:5.27

testis:5.61

heart:5.54

muscle:5.39

esophagus:5.37

stomach:5.66

intestine:5.85

colon:6.02

liver/hepato:6.85

lung:6.91

bladder:-

kidney:5.76

pituitary:5.36

thyroid/parathyroid:5.92

adrenal gland:6.02

pancreas:5.33

breast:5.51

salivary:5.59

CAGE

uterus:1.62

placenta:3.55

prostate:1.53

ovary:1.85

testis:1.58

heart:1.44

muscle:0.99

esophagus:1.08

stomach:-

intestine:2.79

colon:2.42

liver/hepato:2.68

lung:1.82

bladder:1.09

kidney:1.26

pituitary:1.05

thyroid/parathyroid:1.17

adrenal gland:-

pancreas:1.74

breast:2.74

salivary:2.26

RNA-seq

uterus:-

placenta:-

prostate:0.31

ovary:1.21

testis:1.27

heart:0.28

muscle:0.02

esophagus:-

stomach:-

intestine:-

colon:0.34

liver/hepato:0.59

lung:0.83

bladder:-

kidney:0.18

pituitary:-

thyroid/parathyroid:1.77

adrenal gland:1.29

pancreas:-

breast:1.49

salivary:-

IDs

Refseq ID	NM_194255
Gene ID	6573
Unigene ID	Hs.84190
Probe set ID	211576_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000173638
GTEx ID	ENSG00000173638

Orthologous Gene

Mouse[2]	NM_001199271, NM_031196
Rat [0]

Chromosomal Region

21q22.3 [46,913,486 - 46,964,316]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016196	Major facilitator superfamily, general substrate transporter
IPR002666	Reduced folate carrier

Gene Ontology (GO ID)

Biological Process

GO:0046655	folic acid metabolic process
GO:0015884	folic acid transport
GO:0051958	methotrexate transport
GO:0006766	vitamin metabolic process
GO:0006767	water-soluble vitamin metabolic process

Cellular Component

GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005542	folic acid binding
GO:0008517	folic acid transporter activity
GO:0015350	methotrexate transporter activity
GO:0008518	reduced folate carrier activity

solute carrier family 19 (folate transporter), member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function