delta-like 2 homolog (Drosophila)

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Synonym

Multiple EGF-like domain protein 9, EGF-like domain-containing protein 9 precursor, MGC111055, UNQ2903/PRO28633, EGFL9, EGF-like-domain, multiple 9, MGC2487

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:7.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:5.62 cerebellum:5.86 brain stem:5.36 corpus callosum/glia:5.51 pineal gland:- peripheral nerve:5.64 spine:5.40 retina:- eye:- artery/aorta:5.64 vein:5.73 lymphnode:5.61 peripheral blood:- spleen:5.26 thymus:5.90 bone marrow:5.78 adipose:5.58 bone:- skin:5.99
CAGE cerebrum:1.30 cerebellum:- brain stem:0.40 corpus callosum/glia:0.63 pineal gland:0.14 peripheral nerve:- spine:0.46 retina:- eye:- artery/aorta:0.18 vein:0.88 lymphnode:0.87 peripheral blood:- spleen:0 thymus:0.64 bone marrow:- adipose:0.36 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.36 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:7.30 prostate:67.60 ovary:37.30 testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.48 placenta:5.37 prostate:5.92 ovary:5.36 testis:5.51 heart:5.39 muscle:5.55 esophagus:6.06 stomach:5.27 intestine:5.78 colon:5.43 liver/hepato:5.41 lung:5.51 bladder:- kidney:5.34 pituitary:5.69 thyroid/parathyroid:5.48 adrenal gland:5.49 pancreas:6.07 breast:6.05 salivary:6.22
CAGE uterus:0.65 placenta:0 prostate:1.66 ovary:0.79 testis:0.52 heart:0.32 muscle:0 esophagus:1.70 stomach:- intestine:0.14 colon:0.39     liver/hepato:0.26    lung:0.35 bladder:0 kidney:0.08 pituitary:0.71 thyroid/parathyroid:0.37 adrenal gland:- pancreas:0.58 breast:1.68 salivary:1.39
RNA-seq uterus:- placenta:- prostate:0.24 ovary:0.00 testis:0.00 heart:0.08 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.02        lung:0.18    bladder:- kidney:0.08 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.17 salivary:-

Gene Information

IDs

Refseq ID NM_023932
Gene ID 65989
Unigene ID Hs.337251
Probe set ID 220262_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171462
GTEx ID ENSG00000171462

Orthologous Gene

Mouse[2]  NM_207666
Rat[1]  NM_001108202

Chromosomal Region

6p21.1  [43,418,090  -  43,424,370]

Gene Family (Interpro ID)

IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

12477932
12975309
14574404
14702039
15489334
16189514
16344560
17320102
21832049

Gene Ontology  (GO ID)

Biological Process

GO:0045746  negative regulation of Notch signaling pathway
GO:0045598  regulation of fat cell differentiation

Cellular Component

GO:0016021  integral to membrane

Molecular Function

GO:0005509  calcium ion binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity