suppression of tumorigenicity 5

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Synonym

ST5, DENN domain-containing protein 2B, HTS1, MGC33090, HeLa tumor suppression 1, DENND2B, Suppression of tumorigenicity 5, suppression of tumorigenicity 5, p126

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:90.10 cerebellum:277.10 brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:92 spine:112.30 retina:118.60 eye:99.90 artery/aorta:- vein:133.30 lymphnode:20.20 peripheral blood:- spleen:302.50 thymus:25.80 bone marrow:157.40 adipose:121 bone:51.20 skin:96
GeneChip cerebrum:6.48 cerebellum:6.37 brain stem:6.49 corpus callosum/glia:6.68 pineal gland:- peripheral nerve:7.10 spine:6.83 retina:- eye:- artery/aorta:7.57 vein:8.03 lymphnode:6.77 peripheral blood:- spleen:8 thymus:5.91 bone marrow:5.68 adipose:6.94 bone:- skin:6.86
CAGE cerebrum:3.45 cerebellum:- brain stem:3.12 corpus callosum/glia:3.81 pineal gland:4.37 peripheral nerve:- spine:3.42 retina:- eye:- artery/aorta:3.94 vein:3.35 lymphnode:3.12 peripheral blood:- spleen:4.17 thymus:2.52 bone marrow:- adipose:2.96 bone:- skin:-
RNA-seq cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.58 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.63 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:656.20 placenta:196.70 prostate:90.10 ovary:260.80 testis:402.40 heart:63.90 muscle:20.10 esophagus:- stomach:127.50 intestine:- colon:144.20     liver/hepato:42.20        lung:205.30    bladder:628.10 kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:80 breast:167.30 salivary:-
GeneChip uterus:8.61 placenta:7.14 prostate:7.55 ovary:8.60 testis:8.41 heart:6.98 muscle:6.64 esophagus:7.47 stomach:7.84 intestine:7.20 colon:7.55 liver/hepato:6.93 lung:7.08 bladder:- kidney:6.51 pituitary:7.23 thyroid/parathyroid:7.58 adrenal gland:7.90 pancreas:6.24 breast:7.76 salivary:7.26
CAGE uterus:5.25 placenta:4.03 prostate:4.39 ovary:4.99 testis:4.71 heart:3.56 muscle:2.88 esophagus:4.25 stomach:- intestine:3.99 colon:4.33     liver/hepato:2.95    lung:3.56 bladder:4.40 kidney:3.48 pituitary:3.68 thyroid/parathyroid:3.47 adrenal gland:- pancreas:3.71 breast:3.43 salivary:4.35
RNA-seq uterus:- placenta:- prostate:5.04 ovary:5.07 testis:4.42 heart:2.64 muscle:1.87 esophagus:- stomach:- intestine:- colon:4.01     liver/hepato:2.32        lung:3.68    bladder:- kidney:2.86 pituitary:- thyroid/parathyroid:3.02 adrenal gland:3.48 pancreas:- breast:2.74 salivary:-

Gene Information

IDs

Refseq ID NM_139157
Gene ID 6764
Unigene ID Hs.117715
Probe set ID 202440_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000166444
GTEx ID ENSG00000166444

Orthologous Gene

Mouse[2]  NM_001001326, NM_029811
Rat[1]  NM_001107547, NM_029811

Chromosomal Region

11p15.4  [8,714,898  -  8,932,498]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1390339
8972856
9632734
10229203
10692462
11528127
12477932
15231748
15489334
15778465
17081983
19843505
19850743
20379614
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0070374  positive regulation of ERK1 and ERK2 cascade

Molecular Function

GO:0017112  Rab guanyl-nucleotide exchange factor activity