urocortin

 jump to detail

Synonym

UROC, UCN, UI, MGC129975, Urocortin precursor, urocortin, MGC129974

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.03 cerebellum:4.79 brain stem:4.86 corpus callosum/glia:4.89 pineal gland:- peripheral nerve:4.65 spine:4.53 retina:- eye:- artery/aorta:4.43 vein:4.82 lymphnode:4.50 peripheral blood:- spleen:4.24 thymus:4.48 bone marrow:4.41 adipose:4.47 bone:- skin:4.63
CAGE nodata
RNA-seq cerebrum:0.59 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.98 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.10 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:3.60 prostate:- ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:9.80    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:- salivary:-
GeneChip uterus:4.45 placenta:4.47 prostate:4.28 ovary:4.70 testis:4.40 heart:4.68 muscle:4.83 esophagus:4.40 stomach:4.40 intestine:4.44 colon:4.47 liver/hepato:4.76 lung:4.51 bladder:- kidney:4.38 pituitary:4.49 thyroid/parathyroid:4.39 adrenal gland:4.87 pancreas:5.09 breast:4.66 salivary:4.50
CAGE nodata
RNA-seq uterus:- placenta:- prostate:1.39 ovary:0.26 testis:0.47 heart:0.28 muscle:0.17 esophagus:- stomach:- intestine:- colon:0.13     liver/hepato:0.51        lung:0.19    bladder:- kidney:0.39 pituitary:- thyroid/parathyroid:0.53 adrenal gland:0.46 pancreas:- breast:0.29 salivary:-

Gene Information

IDs

Refseq ID NM_003353
Gene ID 7349
Unigene ID Hs.534363
Probe set ID 206072_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000163794
GTEx ID ENSG00000163794

Orthologous Gene

Mouse[1]  NM_021290
Rat [0]  

Chromosomal Region

2p23.3  [27,530,268  -  27,531,313]

Gene Family (Interpro ID)

IPR000187  Corticotropin-releasing factor, CRF

Link to Pubmed  (Pubmed ID)

861256
8612563
8612576
9360550
9423932
9467598
9622018
9628819
10341863
10422876
10690896
11150640
11238533
11329063
11416224
11788672
11836334
12010647
12111693
12175707
12477932
12519893
12535698
14519439
14576187
14764822
15072543
15489334
15784504
15815621
15924674
16340217
16675846
16698078
16920724
17154253
17597629
18234674
18329817
18443956
18670748
19086053
19437022
19619932
19703147
19808377
19893766
19949969
19961889
20363214
20368512
20468064
20480172
20670842
21289256
21360527
22639902
23128233
23416839
23801677
23803006
23846219
23987517
24012814
24290358

Gene Ontology  (GO ID)

Biological Process

GO:0034199  activation of protein kinase A activity
GO:0009060  aerobic respiration
GO:0008306  associative learning
GO:0042756  drinking behavior
GO:0007565  female pregnancy
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0006954  inflammatory response
GO:0043066  negative regulation of apoptosis
GO:0032099  negative regulation of appetite
GO:0045776  negative regulation of blood pressure
GO:0045792  negative regulation of cell size
GO:0060455  negative regulation of gastric acid secretion
GO:0010629  negative regulation of gene expression
GO:0046888  negative regulation of hormone secretion
GO:0031175  neuron projection development
GO:0007218  neuropeptide signaling pathway
GO:0030157  pancreatic juice secretion
GO:0051461  positive regulation of adrenocorticotropin secretion
GO:0030819  positive regulation of cAMP biosynthetic process
GO:0060452  positive regulation of cardiac muscle contraction
GO:0030307  positive regulation of cell growth
GO:0032967  positive regulation of collagen biosynthetic process
GO:0045740  positive regulation of DNA replication
GO:0010628  positive regulation of gene expression
GO:0032755  positive regulation of interleukin-6 production
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0045727  positive regulation of translation
GO:0043117  positive regulation of vascular permeability
GO:0045909  positive regulation of vasodilation
GO:0051966  regulation of synaptic transmission, glutamatergic
GO:0032355  response to estradiol stimulus
GO:0051384  response to glucocorticoid stimulus
GO:0006979  response to oxidative stress
GO:0048265  response to pain

Cellular Component

GO:0030425  dendrite
GO:0005576  extracellular region
GO:0043679  nerve terminal
GO:0043204  perikaryon
GO:0043196  varicosity

Molecular Function

GO:0051430  corticotropin-releasing hormone receptor 1 binding
GO:0051431  corticotropin-releasing hormone receptor 2 binding
GO:0046811  histone deacetylase inhibitor activity
GO:0005184  neuropeptide hormone activity
GO:0005515  protein binding