capping protein (actin filament), gelsolin-like

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Synonym

AFCP, Macrophage capping protein, capping protein (actin filament), gelsolin-like, Actin-regulatory protein CAP-G, CAPG

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:14.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:52.90 artery/aorta:- vein:- lymphnode:80.90 peripheral blood:419 spleen:18.90 thymus:- bone marrow:- adipose:40.30 bone:38.40 skin:48
GeneChip cerebrum:5.68 cerebellum:5.50 brain stem:5.85 corpus callosum/glia:6.57 pineal gland:- peripheral nerve:5.77 spine:6.67 retina:- eye:- artery/aorta:6.23 vein:6.05 lymphnode:7.25 peripheral blood:- spleen:5.95 thymus:6.92 bone marrow:7.90 adipose:6.83 bone:- skin:7.59
CAGE cerebrum:1.80 cerebellum:- brain stem:2.37 corpus callosum/glia:2.88 pineal gland:0.83 peripheral nerve:- spine:2.67 retina:- eye:- artery/aorta:2.92 vein:3.29 lymphnode:3.51 peripheral blood:- spleen:2.37 thymus:2.89 bone marrow:- adipose:3.82 bone:- skin:-
RNA-seq cerebrum:0.99 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.65 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:82 placenta:36.40 prostate:123.90 ovary:111.80 testis:17.30 heart:12.80 muscle:20.10 esophagus:- stomach:21.20 intestine:- colon:59.40     liver/hepato:52.80        lung:97.80    bladder:- kidney:93.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:53.30 breast:46.50 salivary:-
GeneChip uterus:6.46 placenta:6.18 prostate:7.11 ovary:6.18 testis:6.23 heart:5.54 muscle:5.26 esophagus:8.30 stomach:6.46 intestine:6.25 colon:6.62 liver/hepato:5.21 lung:8.61 bladder:- kidney:7.35 pituitary:5.67 thyroid/parathyroid:7.99 adrenal gland:5.64 pancreas:6.38 breast:7.62 salivary:6.04
CAGE uterus:2.92 placenta:2.76 prostate:2.82 ovary:2.37 testis:2.44 heart:1.17 muscle:0.86 esophagus:3.81 stomach:- intestine:2.41 colon:2.75     liver/hepato:0.90    lung:4.04 bladder:2.81 kidney:3.44 pituitary:1.60 thyroid/parathyroid:3.37 adrenal gland:- pancreas:2.26 breast:2.59 salivary:2.22
RNA-seq uterus:- placenta:- prostate:1.10 ovary:2.20 testis:0.77 heart:0.00 muscle:0.47 esophagus:- stomach:- intestine:- colon:0.48     liver/hepato:0.00        lung:2.47    bladder:- kidney:0.63 pituitary:- thyroid/parathyroid:1.59 adrenal gland:1.89 pancreas:- breast:1.64 salivary:-

Gene Information

IDs

Refseq ID NM_001747
Gene ID 822
Unigene ID Hs.516155
Probe set ID 201850_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000042493
GTEx ID ENSG00000042493

Orthologous Gene

Mouse[2]  NM_001042534, NM_007599
Rat [0]  

Chromosomal Region

2p11.2  [85,621,346  -  85,645,555]

Gene Family (Interpro ID)

IPR007122  Gelsolin

Link to Pubmed  (Pubmed ID)

1322908
7814409
7851883
8125298
9160743
11337467
11694586
12477932
12637565
12754261
15454578
15489334
16767159
17081065
18029348
18059028
18237446
18266911
18461482
18709641
18938132
19011242
19056867
19166812
19188659
19242827
19439302
19454010
21768101
21906983
21908955
22155129
22190510
23085225
23782053
23874603
24654937

Gene Ontology  (GO ID)

Biological Process

GO:0051016  barbed-end actin filament capping
GO:0030031  cell projection assembly
GO:0006461  protein complex assembly

Cellular Component

GO:0005737  cytoplasm
GO:0008290  F-actin capping protein complex
GO:0042470  melanosome
GO:0031965  nuclear membrane
GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0003779  actin binding