runt-related transcription factor 3

Synonym

FLJ34510, MGC16070, runt-related transcription factor 3, PEBP2aC, CBF-alpha 3, Runt-related transcription factor 3, RUNX3, PEBP2-alpha C, Acute myeloid leukemia 2 protein, Core-binding factor, alpha 3 subunit, CBFA3, PEA2-alpha C, SL3-3 enhancer factor 1 alpha C subunit, PEBP2A3, AML2, SL3/AKV core-binding factor alpha C subunit, Oncogene AML-2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:4.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:17.60

artery/aorta:-

vein:-

lymphnode:283.10

peripheral blood:91.10

spleen:94.50

thymus:90.20

bone marrow:98.40

adipose:40.30

bone:12.80

skin:14.40

GeneChip

cerebrum:4.79

cerebellum:4.88

brain stem:4.74

corpus callosum/glia:4.90

pineal gland:-

peripheral nerve:5.24

spine:5.12

retina:-

eye:-

artery/aorta:5.18

vein:5.28

lymphnode:7.43

peripheral blood:-

spleen:7.70

thymus:5.82

bone marrow:6.24

adipose:5.60

bone:-

skin:6.20

CAGE

cerebrum:0.62

cerebellum:-

brain stem:1.42

corpus callosum/glia:1.29

pineal gland:0.92

peripheral nerve:-

spine:1.66

retina:-

eye:-

artery/aorta:2.79

vein:3.72

lymphnode:4.22

peripheral blood:-

spleen:4.03

thymus:3.14

bone marrow:-

adipose:1.66

bone:-

skin:-

RNA-seq

cerebrum:0.25

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.09

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.66

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:54.70

placenta:-

prostate:56.30

ovary:-

testis:4.30

heart:89.40

muscle:-

esophagus:-

stomach:-

intestine:-

colon:42.40

liver/hepato:-

lung:34.20

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.97

placenta:4.94

prostate:4.83

ovary:4.81

testis:5.04

heart:4.77

muscle:4.77

esophagus:5.34

stomach:5.61

intestine:5.30

colon:5.54

liver/hepato:5.32

lung:6.07

bladder:-

kidney:4.78

pituitary:4.76

thyroid/parathyroid:5.13

adrenal gland:5.12

pancreas:5.02

breast:5.85

salivary:5.01

CAGE

uterus:2.01

placenta:1.20

prostate:1.81

ovary:1.35

testis:1.53

heart:0.88

muscle:0.84

esophagus:2.08

stomach:-

intestine:3.16

colon:2.76

liver/hepato:1.51

lung:3.35

bladder:2.89

kidney:1.40

pituitary:0.66

thyroid/parathyroid:1.17

adrenal gland:-

pancreas:1.21

breast:2.19

salivary:1.82

RNA-seq

uterus:-

placenta:-

prostate:0.60

ovary:0.24

testis:1.38

heart:0.32

muscle:0.25

esophagus:-

stomach:-

intestine:-

colon:0.55

liver/hepato:0.00

lung:3.07

bladder:-

kidney:0.43

pituitary:-

thyroid/parathyroid:0.31

adrenal gland:3.34

pancreas:-

breast:0.96

salivary:-

IDs

Refseq ID	NM_004350
Gene ID	864
Unigene ID	Hs.170019
Probe set ID	204197_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000020633
GTEx ID	ENSG00000020633

Orthologous Gene

Mouse[1]	NM_019732
Rat[1]	NM_130425

Chromosomal Region

1p36.11 [25,226,002 - 25,291,612]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR013524	Acute myeloid leukemia 1 (AML 1)/Runt
IPR000040	Acute myeloid leukemia 1 protein (AML 1)/Runt
IPR008967	p53-like transcription factor, DNA-binding
IPR012346	p53/RUNT-type transcription factor, DNA-binding domain
IPR016554	Transcription factor, Runt-related, RUNX

GO:0007411	axon guidance
GO:0048469	cell maturation
GO:0002062	chondrocyte differentiation
GO:0031069	hair follicle morphogenesis
GO:0032609	interferon-gamma production
GO:0045786	negative regulation of cell cycle
GO:0050680	negative regulation of epithelial cell proliferation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0048935	peripheral nervous system neuron development
GO:0006468	protein amino acid phosphorylation
GO:0006355	regulation of transcription, DNA-dependent
GO:0006366	transcription from RNA polymerase II promoter

GO:0005737	cytoplasm
GO:0000790	nuclear chromatin
GO:0005634	nucleus

GO:0005524	ATP binding
GO:0005515	protein binding
GO:0003700	transcription factor activity

runt-related transcription factor 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function