polycystic kidney disease 2-like 1

 jump to detail

Synonym

Polycystin-2 homolog, PCL, Polycystin-L, polycystic kidney disease 2-like 1, Polycystic kidney disease 2-like 1 protein, PKD2L1, PKD2L, PKDL

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:23.50 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.38 cerebellum:6.45 brain stem:6.36 corpus callosum/glia:6.34 pineal gland:- peripheral nerve:6.18 spine:6.22 retina:- eye:- artery/aorta:6.31 vein:6.51 lymphnode:6.26 peripheral blood:- spleen:6.19 thymus:6.16 bone marrow:6.46 adipose:6.39 bone:- skin:6.45
CAGE cerebrum:0.29 cerebellum:- brain stem:0.03 corpus callosum/glia:0.07 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.37 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.36 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.05 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:8.70 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.24 placenta:6.53 prostate:6.11 ovary:6.29 testis:6.26 heart:6.22 muscle:6.38 esophagus:6.15 stomach:6.08 intestine:6.37 colon:6.26 liver/hepato:6.22 lung:6.29 bladder:- kidney:6.12 pituitary:6.17 thyroid/parathyroid:6.08 adrenal gland:6.10 pancreas:6.56 breast:6.18 salivary:6.23
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0.07 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.05 ovary:0.11 testis:0.18 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.04        lung:0.12    bladder:- kidney:0.11 pituitary:- thyroid/parathyroid:0 adrenal gland:0.20 pancreas:- breast:0.03 salivary:-

Gene Information

IDs

Refseq ID NM_016112
Gene ID 9033
Unigene ID Hs.159241
Probe set ID 221061_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000107593
GTEx ID ENSG00000107593

Orthologous Gene

Mouse[1]  NM_181422
Rat[1]  NM_001106352

Chromosomal Region

10q24.31  [102,047,903  -  102,090,243]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9748274
9878261
10097141
10517637
10602361
10602992
11698076
11805156
11959145
12477932
12525172
12809519
15489334
16385451
16537653
17944866
19812697
20406802
20408813
21886157
22174419
22193359
22359512
22794107
23251661
23362303

Gene Ontology  (GO ID)

Biological Process

GO:0070588  calcium ion transmembrane transport
GO:0006812  cation transport
GO:0071468  cellular response to acidity
GO:0001581  detection of chemical stimulus involved in sensory perception of sour taste
GO:0050982  detection of mechanical stimulus

Cellular Component

GO:0009986  cell surface
GO:0005783  endoplasmic reticulum
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0005886  plasma membrane

Molecular Function

GO:0051393  alpha-actinin binding
GO:0005227  calcium activated cation channel activity
GO:0005262  calcium channel activity
GO:0005509  calcium ion binding
GO:0015269  calcium-activated potassium channel activity
GO:0005261  cation channel activity
GO:0008324  cation transmembrane transporter activity
GO:0008092  cytoskeletal protein binding
GO:0042802  identical protein binding
GO:0051371  muscle alpha-actinin binding
GO:0005515  protein binding
GO:0005272  sodium channel activity
GO:0033040  sour taste receptor activity