aspartoacylase (aminocyclase) 3

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Synonym

HCBP1, ACY-3, Aminoacylase-3, Acylase III, aspartoacylase (aminocyclase) 3, Aspartoacylase-2, ACY3, ASPA2, Hepatitis C virus core-binding protein 1, MGC9740

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:1.40 cerebellum:- brain stem:2.01 corpus callosum/glia:3.49 pineal gland:0.21 peripheral nerve:- spine:1.22 retina:- eye:- artery/aorta:0 vein:0.79 lymphnode:0.99 peripheral blood:- spleen:0.25 thymus:0.83 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.75 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.66 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:32.40 colon:-     liver/hepato:-        lung:-    bladder:- kidney:104 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:0.93 placenta:0.16 prostate:0.39 ovary:0.32 testis:0.25 heart:0.09 muscle:0 esophagus:0 stomach:- intestine:4.96 colon:2.46     liver/hepato:2.91    lung:0.14 bladder:0 kidney:3.36 pituitary:0.19 thyroid/parathyroid:0 adrenal gland:- pancreas:2.86 breast:0 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.13 ovary:0.17 testis:0.30 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.42     liver/hepato:2.08        lung:0.03    bladder:- kidney:2.07 pituitary:- thyroid/parathyroid:0.07 adrenal gland:0.64 pancreas:- breast:0.12 salivary:-

Gene Information

IDs

Refseq ID NM_080658
Gene ID 91703
Unigene ID Hs.126265
Probe set ID -
Ensembl ID ENSG00000132744
GTEx ID ENSG00000132744

Orthologous Gene

Mouse[1]  NM_027857
Rat[1]  NM_001009603

Chromosomal Region

11q13.2  [67,410,026  -  67,418,130]

Gene Family (Interpro ID)

IPR016708  Aspartoacylase
IPR007036  Succinylglutamate desuccinylase/aspartoacylase

Link to Pubmed  (Pubmed ID)

12477932
14656720
15489334
17207965
19056867
19486448
19664597
21988832

Gene Ontology  (GO ID)

Biological Process

GO:0019048  virus-host interaction

Cellular Component

GO:0016324  apical plasma membrane
GO:0005737  cytoplasm

Molecular Function

GO:0004046  aminoacylase activity
GO:0016788  hydrolase activity, acting on ester bonds
GO:0042802  identical protein binding
GO:0046872  metal ion binding