homer homolog 2 (Drosophila)

 jump to detail

Synonym

Homer protein homolog 2, HOMER-2A, Vesl-2, Cupidin, homer homolog 2 (Drosophila), Homer-2, HOMER-2, CPD, ACPD, HOMER2A, HOMER-2B, HOMER2, HOMER2B

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.50 cerebellum:50.40 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:58.80 artery/aorta:30 vein:- lymphnode:- peripheral blood:18.20 spleen:18.90 thymus:12.90 bone marrow:39.40 adipose:80.70 bone:- skin:72
GeneChip cerebrum:4.66 cerebellum:4.59 brain stem:4.64 corpus callosum/glia:4.30 pineal gland:- peripheral nerve:5.04 spine:4.55 retina:- eye:- artery/aorta:4.33 vein:4.42 lymphnode:4.43 peripheral blood:- spleen:4.50 thymus:4.12 bone marrow:4.71 adipose:4.67 bone:- skin:5.68
CAGE cerebrum:2.88 cerebellum:- brain stem:2.76 corpus callosum/glia:3.09 pineal gland:3.40 peripheral nerve:- spine:3.28 retina:- eye:- artery/aorta:2.74 vein:2.06 lymphnode:2.42 peripheral blood:- spleen:2.39 thymus:1.89 bone marrow:- adipose:1.63 bone:- skin:-
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:101.40 ovary:- testis:17.30 heart:51.10 muscle:- esophagus:- stomach:63.70 intestine:- colon:8.50     liver/hepato:-        lung:29.30    bladder:125.60 kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:44.50 breast:37.20 salivary:-
GeneChip uterus:4.73 placenta:4.18 prostate:7.22 ovary:4.80 testis:5.11 heart:5.27 muscle:6.81 esophagus:6.12 stomach:5.55 intestine:6.02 colon:4.66 liver/hepato:6.24 lung:4.46 bladder:- kidney:4.91 pituitary:4.80 thyroid/parathyroid:5.59 adrenal gland:4.60 pancreas:7.35 breast:5.61 salivary:7.39
CAGE uterus:2.46 placenta:0.99 prostate:4.20 ovary:2.18 testis:2.43 heart:3.19 muscle:4.59 esophagus:2.79 stomach:- intestine:1.64 colon:2.21     liver/hepato:3.98    lung:2.60 bladder:1.56 kidney:2.54 pituitary:3.34 thyroid/parathyroid:3.76 adrenal gland:- pancreas:5.34 breast:3.16 salivary:4.87
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_199331
Gene ID 9455
Unigene ID Hs.578443
Probe set ID 217080_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000103942
GTEx ID ENSG00000103942

Orthologous Gene

Mouse[6]  NM_001164086, NM_001164087, NM_011983
Rat [0]  

Chromosomal Region

15q25.2  [83,517,738  -  83,621,473]

Gene Family (Interpro ID)

IPR000697  EVH1
IPR011993  Pleckstrin homology-type

Link to Pubmed  (Pubmed ID)

8889548
9069287
9808458
9808459
10653696
12223488
12378015
12477932
12676529
12815733
14528310
15489334
15944415
16314758
18029348
18218901
18387811
19086053
19914345
20333726
20531441
20921022
21103663
21636702
21832049
21885651
21988832
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0048148  behavioral response to cocaine
GO:0048875  chemical homeostasis within a tissue
GO:0007216  metabotropic glutamate receptor signaling pathway
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway

Cellular Component

GO:0045177  apical part of cell
GO:0030054  cell junction
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane

Molecular Function

GO:0003779  actin binding
GO:0030160  GKAP/Homer scaffold activity
GO:0035256  metabotropic glutamate receptor binding
GO:0019904  protein domain specific binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity