jumonji domain containing 6

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Synonym

Kiaa0585, Phosphatidylserine receptor, PtdSerR, Ptdsr, PSR, mKIAA0585, D11Ertd195e, Apoptotic cell clearance receptor PtdSerR, phosphatidylserine receptor, Protein PTDSR, 5730436I23Rik

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.18 cerebellum:6.29 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.91 spine:6.30 retina:5.46 eye:5.19 artery/aorta:- vein:6.94 lymphnode:6.80 peripheral blood:- spleen:6.75 thymus:- bone marrow:6.83 adipose:6.60 bone:5.97 skin:5.04
CAGE cerebrum:3.24 cerebellum:- brain stem:3.17 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.88 retina:- eye:- artery/aorta:3.13 vein:- lymphnode:3.48 peripheral blood:- spleen:3.16 thymus:3.50 bone marrow:- adipose:- bone:3.32 skin:3.21
RNA-seq cerebrum:3.64 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.65 placenta:7.04 prostate:6.34 ovary:6.51 testis:8.80 heart:6.81 muscle:7.09 esophagus:- stomach:6.54 intestine:6.66 colon:- liver/hepato:6.93 lung:6.86 bladder:6.46 kidney:6.57 pituitary:6.89 thyroid/parathyroid:- adrenal gland:5.65 pancreas:6.35 breast:6.48 salivary:5.47
CAGE uterus:3.17 placenta:3.53 prostate:2.98 ovary:3.07 testis:5.35 heart:- muscle:- esophagus:- stomach:3.00 intestine:3.32 colon:3.26     liver/hepato:3.41    lung:3.23 bladder:2.82 kidney:- pituitary:3.47 thyroid/parathyroid:- adrenal gland:3.04 pancreas:3.71 breast:3.26 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:3.48 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.97        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_033398
Gene ID 107817
Unigene ID -
Probe set ID 1454109_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000056962

Orthologous Gene

Human[4]  NM_001081461, NM_015167
Rat[4]  NM_001081461, NM_015167

Chromosomal Region

-

Gene Family (Interpro ID)

IPR003347  Transcription factor jumonji/aspartyl beta-hydroxylase

Link to Pubmed  (Pubmed ID)

10349636
10725249
10811223
10922068
11042159
11076861
11217851
12114511
12466851
12477932
12520002
12693553
14610273
14645847
14715629
14729065
15193161
15345036
15453906
15489334
15615595
15618518
15647754
15747579
16141072
16141073
16317002
16602821
16983801
18564434
18799693
20412781
21060799
21267068
21300889
21677750
23303181
23918400

Gene Ontology  (GO ID)

Biological Process

GO:0043277  apoptotic cell clearance
GO:0001568  blood vessel development
GO:0030154  cell differentiation
GO:0007166  cell surface receptor linked signal transduction
GO:0016568  chromatin modification
GO:0048821  erythrocyte development
GO:0007507  heart development
GO:0070078  histone H3-R2 demethylation
GO:0070079  histone H4-R3 demethylation
GO:0001822  kidney development
GO:0030324  lung development
GO:0042116  macrophage activation
GO:0006397  mRNA processing
GO:0007275  multicellular organismal development
GO:0055114  oxidation reduction
GO:0018395  peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
GO:0070782  phosphatidylserine exposure on apoptotic cell surface
GO:0043654  recognition of apoptotic cell
GO:0048024  regulation of nuclear mRNA splicing, via spliceosome
GO:0006355  regulation of transcription, DNA-dependent
GO:0060041  retina development in camera-type eye
GO:0008380  RNA splicing
GO:0002040  sprouting angiogenesis
GO:0033077  T cell differentiation in the thymus
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0033746  histone demethylase activity (H3-R2 specific)
GO:0033749  histone demethylase activity (H4-R3 specific)
GO:0042802  identical protein binding
GO:0005506  iron ion binding
GO:0046872  metal ion binding
GO:0016491  oxidoreductase activity
GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0070815  peptidyl-lysine 5-dioxygenase activity
GO:0005515  protein binding
GO:0004872  receptor activity
GO:0003723  RNA binding
GO:0003727  single-stranded RNA binding