cholinergic receptor, nicotinic, alpha polypeptide 4

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Synonym

Acra-4, ENFL1, Acra4, Chrna4, alpha4 nAChR, a4 nicotinic receptor, EBN1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:97.20

cerebellum:18.40

brain stem:63.60

corpus callosum/glia:-

pineal gland:-

peripheral nerve:76.40

spine:-

retina:-

eye:53.20

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:26.30

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.52

cerebellum:5.12

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.76

spine:5.96

retina:5.35

eye:5.70

artery/aorta:-

vein:4.86

lymphnode:4.66

peripheral blood:-

spleen:5.01

thymus:-

bone marrow:4.77

adipose:4.96

bone:4.85

skin:4.98

CAGE

cerebrum:1.81

cerebellum:-

brain stem:3.54

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:3.46

retina:-

eye:-

artery/aorta:0

vein:-

lymphnode:0

peripheral blood:-

spleen:0

thymus:0.27

bone marrow:-

adipose:-

bone:0

skin:0.84

RNA-seq

cerebrum:4.08

cerebellum:4.08

brain stem:4.08

corpus callosum/glia:4.08

pineal gland:4.08

peripheral nerve:4.08

spine:4.08

retina:4.08

eye:4.08

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:23

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:35.20

liver/hepato:-

lung:-

bladder:-

kidney:40.30

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.69

placenta:5.02

prostate:4.83

ovary:4.84

testis:5.59

heart:5.39

muscle:5.53

esophagus:-

stomach:5.05

intestine:4.92

colon:-

liver/hepato:5.21

lung:4.63

bladder:4.84

kidney:6.81

pituitary:5.17

thyroid/parathyroid:-

adrenal gland:4.85

pancreas:5.84

breast:4.85

salivary:5.18

CAGE

uterus:0.17

placenta:0.80

prostate:0

ovary:1.86

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0.23

colon:0

liver/hepato:0.47

lung:0

bladder:0

kidney:-

pituitary:1.40

thyroid/parathyroid:-

adrenal gland:2.26

pancreas:0

breast:0.20

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_015730
Gene ID	11438
Unigene ID	Mm.252369
Probe set ID	1421202_at [Mouse430_2]
Ensembl ID	ENSMUSG00000027577

Orthologous Gene

Human[3]	NM_000744
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR006201

Neurotransmitter-gated ion-channel

Gene Ontology (GO ID)

Biological Process

GO:0042113	B cell activation
GO:0035095	behavioral response to nicotine
GO:0006816	calcium ion transport
GO:0006812	cation transport
GO:0050890	cognition
GO:0006281	DNA repair
GO:0034220	ion transmembrane transport
GO:0006811	ion transport
GO:0007626	locomotory behavior
GO:0051899	membrane depolarization
GO:0050877	neurological system process
GO:0051291	protein heterooligomerization
GO:0001508	regulation of action potential
GO:0014059	regulation of dopamine secretion
GO:0060080	regulation of inhibitory postsynaptic membrane potential
GO:0042391	regulation of membrane potential
GO:0007585	respiratory gaseous exchange
GO:0001666	response to hypoxia
GO:0035094	response to nicotine
GO:0006979	response to oxidative stress
GO:0019233	sensory perception of pain
GO:0007165	signal transduction
GO:0007271	synaptic transmission, cholinergic
GO:0006810	transport

Cellular Component

GO:0030054	cell junction
GO:0043025	cell soma
GO:0030425	dendrite
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005892	nicotinic acetylcholine-gated receptor-channel complex
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane
GO:0045202	synapse

Molecular Function

GO:0042166	acetylcholine binding
GO:0015464	acetylcholine receptor activity
GO:0008144	drug binding
GO:0005230	extracellular ligand-gated ion channel activity
GO:0005216	ion channel activity
GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity
GO:0005515	protein binding

cholinergic receptor, nicotinic, alpha polypeptide 4

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function