apolipoprotein C-II

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Synonym

Apo-CII, apolipoprotein C-II, MGC117889, Apolipoprotein C-II precursor, Apoc2, ApoC-II

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.46 cerebellum:4.47 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.32 spine:4.92 retina:4.52 eye:4.90 artery/aorta:- vein:4.35 lymphnode:5.32 peripheral blood:- spleen:5 thymus:- bone marrow:6.13 adipose:4.84 bone:5.76 skin:4.27
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0.17 retina:- eye:- artery/aorta:0.83 vein:- lymphnode:0.83 peripheral blood:- spleen:1.12 thymus:1.50 bone marrow:- adipose:- bone:1.69 skin:0
RNA-seq cerebrum:2.84 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:43.60 placenta:69 prostate:- ovary:- testis:- heart:- muscle:35.50 esophagus:- stomach:32.70 intestine:332.80 colon:634.40     liver/hepato:552.10        lung:80.30    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.14 placenta:9.28 prostate:4.19 ovary:4.40 testis:4.58 heart:4.84 muscle:4.58 esophagus:- stomach:5.39 intestine:7.90 colon:- liver/hepato:11.42 lung:5.86 bladder:4.25 kidney:4.28 pituitary:4.55 thyroid/parathyroid:- adrenal gland:5.02 pancreas:5.32 breast:4.92 salivary:4.70
CAGE uterus:0.83 placenta:4.26 prostate:0.20 ovary:0.88 testis:0 heart:- muscle:- esophagus:- stomach:2.79 intestine:7.82 colon:7.17     liver/hepato:6.57    lung:1.17 bladder:0.46 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:1.61 pancreas:0 breast:0.46 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.38 esophagus:- stomach:- intestine:- colon:-     liver/hepato:82.73        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_009695
Gene ID 11813
Unigene ID Mm.28394
Probe set ID 1418069_at  [Mouse430_2]
Ensembl ID ENSMUSG00000002992

Orthologous Gene

Human[2]  NM_000483
Rat[1]  NM_001085352

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

6099394
7560076
7691714
7916738
8088778
8105016
8276416
8562047
10049364
10073946
10349636
10922068
11002334
11042159
11076861
11217851
12032151
12466851
12477932
12954636
14610273
15210844
15489334
16141072
16141073
16498401
16602821
17683524
18799693
19106236
21059267
21267068
21305474
22323595
22412348
24449835

Gene Ontology  (GO ID)

Biological Process

GO:0033344  cholesterol efflux
GO:0034382  chylomicron remnant clearance
GO:0034384  high-density lipoprotein particle clearance
GO:0016042  lipid catabolic process
GO:0006629  lipid metabolic process
GO:0006869  lipid transport
GO:0042953  lipoprotein transport
GO:0043086  negative regulation of catalytic activity
GO:0032375  negative regulation of cholesterol transport
GO:0045833  negative regulation of lipid metabolic process
GO:0048261  negative regulation of receptor-mediated endocytosis
GO:0010916  negative regulation of very-low-density lipoprotein particle clearance
GO:0033700  phospholipid efflux
GO:0043085  positive regulation of catalytic activity
GO:0045723  positive regulation of fatty acid biosynthetic process
GO:0051006  positive regulation of lipoprotein lipase activity
GO:0010518  positive regulation of phospholipase activity
GO:0060697  positive regulation of phospholipid catabolic process
GO:0010898  positive regulation of triglyceride catabolic process
GO:0006810  transport
GO:0070328  triglyceride homeostasis

Cellular Component

GO:0042627  chylomicron
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0034363  intermediate-density lipoprotein particle
GO:0034362  low-density lipoprotein particle
GO:0034366  spherical high-density lipoprotein particle
GO:0034361  very-low-density lipoprotein particle

Molecular Function

GO:0008047  enzyme activator activity
GO:0055102  lipase inhibitor activity
GO:0008289  lipid binding
GO:0060230  lipoprotein lipase activator activity
GO:0016004  phospholipase activator activity
GO:0043274  phospholipase binding
GO:0042803  protein homodimerization activity