bone morphogenetic protein receptor, type 1B

Synonym

Alk6, Acvrlk6, AV355320, Activin receptor-like kinase 6, ALK-6, Serine/threonine-protein kinase receptor R6, BMPR-IB, SKR6, AI385617, CFK-43a, bone morphogenetic protein receptor, type 1B, Bmpr1b

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:105.90

cerebellum:18.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:19.10

spine:-

retina:96.40

eye:144.40

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:14.40

spleen:39.50

thymus:29.60

bone marrow:-

adipose:-

bone:100.20

skin:39.60

GeneChip

cerebrum:4.34

cerebellum:4.38

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.11

spine:4.60

retina:4.20

eye:4.58

artery/aorta:-

vein:3.92

lymphnode:3.97

peripheral blood:-

spleen:4.29

thymus:-

bone marrow:4.04

adipose:4.39

bone:4.05

skin:3.97

CAGE

cerebrum:1.81

cerebellum:-

brain stem:2.45

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.69

retina:-

eye:-

artery/aorta:2.14

vein:-

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:-

bone:0

skin:1.20

RNA-seq

cerebrum:1.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:87.20

placenta:13.80

prostate:30.90

ovary:23

testis:36.90

heart:-

muscle:-

esophagus:-

stomach:32.70

intestine:-

colon:17.60

liver/hepato:9.10

lung:50.20

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:37.50

breast:35.90

salivary:-

GeneChip

uterus:4.11

placenta:4.08

prostate:6.16

ovary:5.14

testis:4.35

heart:4.34

muscle:4.56

esophagus:-

stomach:4.27

intestine:4.04

colon:-

liver/hepato:4.45

lung:3.88

bladder:4.23

kidney:4.29

pituitary:4.11

thyroid/parathyroid:-

adrenal gland:3.82

pancreas:5.01

breast:4.13

salivary:4.56

CAGE

uterus:1.65

placenta:0.10

prostate:4.70

ovary:3.39

testis:0

heart:-

muscle:-

esophagus:-

stomach:1.35

intestine:0

colon:0.57

liver/hepato:0

lung:2.19

bladder:1.50

kidney:-

pituitary:0.52

thyroid/parathyroid:-

adrenal gland:0.14

pancreas:3.49

breast:0.20

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.13

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007560
Gene ID	12167
Unigene ID	Mm.390895
Probe set ID	1422872_at [Mouse430_2]
Ensembl ID	ENSMUSG00000052430

Orthologous Gene

Human[1]	NM_001203
Rat[1]	NM_001024259

Chromosomal Region

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0030509	BMP signaling pathway
GO:0043010	camera-type eye development
GO:0001502	cartilage condensation
GO:0051216	cartilage development
GO:0030154	cell differentiation
GO:0002062	chondrocyte differentiation
GO:0009953	dorsal/ventral pattern formation
GO:0006703	estrogen biosynthetic process
GO:0001654	eye development
GO:0035108	limb morphogenesis
GO:0001550	ovarian cumulus expansion
GO:0042698	ovulation cycle
GO:0016310	phosphorylation
GO:0030501	positive regulation of bone mineralization
GO:0045597	positive regulation of cell differentiation
GO:0045669	positive regulation of osteoblast differentiation
GO:0006468	protein amino acid phosphorylation
GO:0060041	retina development in camera-type eye
GO:0031290	retinal ganglion cell axon guidance
GO:0001501	skeletal system development
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway

Cellular Component

GO:0016021	integral to membrane
GO:0016020	membrane

Molecular Function

GO:0005524	ATP binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0046332	SMAD binding
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0005024	transforming growth factor beta receptor activity
GO:0005025	transforming growth factor beta receptor activity, type I
GO:0004675	transmembrane receptor protein serine/threonine kinase activity

bone morphogenetic protein receptor, type 1B

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function