cytochrome P450, family 2, subfamily d, polypeptide 9

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Synonym

Cytochrome P450 2D9, Cyp2d-9, Cyp2d9, CA, testosterone 16alpha-hydroxylase, CYPIID9

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:10.80 peripheral blood:- spleen:39.50 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:4.64 cerebellum:5.14 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.22 spine:4.24 retina:4.53 eye:4.54 artery/aorta:- vein:4.27 lymphnode:4.34 peripheral blood:- spleen:4.24 thymus:- bone marrow:4.25 adipose:4.55 bone:4.30 skin:4.36
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:0
RNA-seq cerebrum:17.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:18.60 muscle:142 esophagus:- stomach:- intestine:- colon:141     liver/hepato:2407.30        lung:20.10    bladder:- kidney:403 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:13.10 salivary:378
GeneChip uterus:4.42 placenta:4.34 prostate:4.11 ovary:4.15 testis:4.18 heart:5.02 muscle:4.61 esophagus:- stomach:4.62 intestine:5.05 colon:- liver/hepato:11.82 lung:6.58 bladder:4.45 kidney:8.66 pituitary:4.76 thyroid/parathyroid:- adrenal gland:5.72 pancreas:4.78 breast:4.50 salivary:4.37
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0 colon:0     liver/hepato:0.26    lung:0 bladder:0 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.33 esophagus:- stomach:- intestine:- colon:-     liver/hepato:261.46        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_010006
Gene ID 13105
Unigene ID Mm.226708
Probe set ID 1419349_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000068086

Orthologous Gene

Human[2]  NM_000106, NM_001025161
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001128  Cytochrome P450
IPR002401  Cytochrome P450, E-class, group I
IPR008069  Cytochrome P450, E-class, group I, CYP2D-like
IPR002403  Cytochrome P450, E-class, group IV

Link to Pubmed  (Pubmed ID)

1401899
2788458
2831949
2914938
3582092
3856880
7565685
7623810
7892260
8432535
9027489
9316857
9586588
9630227
10349636
10591541
11042159
11076861
11217851
12466851
12477932
12745259
14563677
14681479
16141072
16141073
21267068

Gene Ontology  (GO ID)

Biological Process

GO:0055114  oxidation reduction

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005739  mitochondrion

Molecular Function

GO:0070330  aromatase activity
GO:0008144  drug binding
GO:0009055  electron carrier activity
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0046872  metal ion binding
GO:0004497  monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0016705  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen