cytochrome P450, family 3, subfamily a, polypeptide 16

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Synonym

Cytochrome P450 3A16, MGC130513, CYPIIIA16, Cyp3a-16, Cyp3a16

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:3.26 cerebellum:3.31 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:3.18 spine:3.32 retina:3.25 eye:3.36 artery/aorta:- vein:3.25 lymphnode:3.28 peripheral blood:- spleen:3.28 thymus:- bone marrow:3.29 adipose:3.24 bone:3.22 skin:3.39
CAGE nodata
RNA-seq cerebrum:7.76 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:106.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:81.50        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.19 placenta:3.30 prostate:3.37 ovary:3.35 testis:3.21 heart:3.25 muscle:3.54 esophagus:- stomach:3.34 intestine:3.28 colon:- liver/hepato:3.48 lung:3.33 bladder:3.35 kidney:3.26 pituitary:3.30 thyroid/parathyroid:- adrenal gland:3.28 pancreas:3.66 breast:3.29 salivary:3.29
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:120.77        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_007820
Gene ID 13114
Unigene ID Mm.378905
Probe set ID 1421741_at  [Mouse430_2]
Ensembl ID ENSMUSG00000038656

Orthologous Gene

Human[19]  NM_022820, NM_057095, NM_057096, NM_000777, NM_001190484, NM_001202855, NM_017460, NM_000765
Rat[3]  NM_145782, NM_153312, NM_147206, NM_013105, NM_001190484, NM_001202855, NM_017460, NM_000765

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001128  Cytochrome P450
IPR002397  Cytochrome P450, B-class
IPR008072  Cytochrome P450, E-class, CYP3A
IPR002401  Cytochrome P450, E-class, group I
IPR002402  Cytochrome P450, E-class, group II
IPR002403  Cytochrome P450, E-class, group IV

Link to Pubmed  (Pubmed ID)

7813478
9048885
12477932
12819125
14509827
19188337
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0055114  oxidation reduction

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane

Molecular Function

GO:0070330  aromatase activity
GO:0032451  demethylase activity
GO:0009055  electron carrier activity
GO:0020037  heme binding
GO:0005506  iron ion binding
GO:0046872  metal ion binding
GO:0004497  monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0016705  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016712  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0050649  testosterone 6-beta-hydroxylase activity