dopamine beta hydroxylase

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Synonym

Dbh, dopamine beta hydroxylase, Dopamine beta-monooxygenase, Dopamine beta-hydroxylase precursor

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:6.90 cerebellum:36.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:172 spine:- retina:- eye:- artery/aorta:337.60 vein:- lymphnode:- peripheral blood:- spleen:- thymus:39.50 bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:5.03 cerebellum:5.04 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:5.13 spine:5.27 retina:5.18 eye:5.61 artery/aorta:- vein:5.01 lymphnode:4.64 peripheral blood:- spleen:5.05 thymus:- bone marrow:4.92 adipose:5.23 bone:5.27 skin:4.89
CAGE cerebrum:0.23 cerebellum:- brain stem:3.07 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:2.87 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0.27 bone marrow:- adipose:- bone:0 skin:0
RNA-seq cerebrum:1.47 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:11.50 testis:- heart:- muscle:71 esophagus:- stomach:- intestine:- colon:35.20     liver/hepato:-        lung:-    bladder:264.70 kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:424.40 pancreas:- breast:- salivary:-
GeneChip uterus:4.80 placenta:5.07 prostate:4.86 ovary:4.58 testis:5.39 heart:6.16 muscle:5.11 esophagus:- stomach:5.23 intestine:5.24 colon:- liver/hepato:5.41 lung:4.81 bladder:4.98 kidney:5.43 pituitary:5.17 thyroid/parathyroid:- adrenal gland:10.58 pancreas:5.50 breast:5.13 salivary:5.32
CAGE uterus:0 placenta:0 prostate:3.34 ovary:0.13 testis:0 heart:- muscle:- esophagus:- stomach:0.67 intestine:1.99 colon:1.72     liver/hepato:0    lung:0 bladder:3.30 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:6.80 pancreas:0 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:0.89 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

IDs

Refseq ID NM_138942
Gene ID 13166
Unigene ID Mm.167781
Probe set ID 1450670_at  [Mouse430_2]
Ensembl ID ENSMUSG00000000889

Orthologous Gene

Human[1]  NM_000787
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0008306  associative learning
GO:0048149  behavioral response to ethanol
GO:0001974  blood vessel remodeling
GO:0042423  catecholamine biosynthetic process
GO:0006584  catecholamine metabolic process
GO:0001816  cytokine production
GO:0042420  dopamine catabolic process
GO:0042596  fear response
GO:0042593  glucose homeostasis
GO:0042309  homoiothermy
GO:0002443  leukocyte mediated immunity
GO:0050900  leukocyte migration
GO:0007626  locomotory behavior
GO:0042711  maternal behavior
GO:0007613  memory
GO:0042421  norepinephrine biosynthetic process
GO:0046333  octopamine metabolic process
GO:0055114  oxidation reduction
GO:0045907  positive regulation of vasoconstriction
GO:0042127  regulation of cell proliferation
GO:0001975  response to amphetamine
GO:0048265  response to pain
GO:0008542  visual learning

Cellular Component

GO:0045177  apical part of cell
GO:0030424  axon
GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0016023  cytoplasmic membrane-bounded vesicle
GO:0031410  cytoplasmic vesicle
GO:0030425  dendrite
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0045202  synapse
GO:0043195  terminal button
GO:0043196  varicosity

Molecular Function

GO:0003824  catalytic activity
GO:0005507  copper ion binding
GO:0004500  dopamine beta-monooxygenase activity
GO:0031418  L-ascorbic acid binding
GO:0046872  metal ion binding
GO:0004497  monooxygenase activity
GO:0016491  oxidoreductase activity
GO:0016715  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen