DNA methyltransferase (cytosine-5) 1

詳細情報を見る

同義遺伝子名

M.MmuI, Dnmt1, DNA (cytosine-5)-methyltransferase 1, Met-1, Uim, Dnmt, DNA MTase MmuI, MCMT, Dnmt1o, Met1, DNA methyltransferase MmuI, Cxxc9, MTase, DNA methyltransferase (cytosine-5) 1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:272.60 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:57.30 脊柱:- 網膜:160.70 目:395.10 動脈:- 静脈:- リンパ節:- 末梢血:201.30 脾臓:52.70 胸腺:19.80 骨髄:64.10 脂肪:- 骨:225.40 皮膚:71.30
GeneChip 大脳:7.78 小脳:8.05 脳幹:- 脳梁:- 松果体:- 末梢神経:7.30 脊柱:7.36 網膜:8.57 目:8.65 動脈:- 静脈:8.76 リンパ節:8.85 末梢血:- 脾臓:8.97 胸腺:- 骨髄:10.72 脂肪:6.79 骨:10.38 皮膚:8.38
CAGE 大脳:3.30 小脳:- 脳幹:3.09 脳梁:- 松果体:- 末梢神経:- 脊柱:3.05 網膜:- 目:- 動脈:2.78 静脈:- リンパ節:4.40 末梢血:- 脾臓:4.58 胸腺:4.71 骨髄:- 脂肪:- 骨:4.29 皮膚:3.90
RNA-seq 大脳:6.12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:130.90 胎盤:41.40 前立腺:- 卵巣:540.10 精巣:199.50 心臓:148.80 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:9.10        肺:130.50    膀胱:66.20 腎臓:72.50 下垂体:271.30 甲状腺:- 副腎:- 膵臓:46.90 乳腺:97.90 唾液腺:-
GeneChip 子宮:8.34 胎盤:8.60 前立腺:7.19 卵巣:8.56 精巣:7.43 心臓:6.58 骨格筋:6.34 食道:- 胃:7.71 腸:8.37 結腸:- 肝臓:5.86 肺:7.74 膀胱:7.17 腎臓:6.67 下垂体:7.10 甲状腺:- 副腎:8.26 膵臓:6.43 乳腺:8.14 唾液腺:7.55
CAGE 子宮:3.19 胎盤:4.18 前立腺:2.51 卵巣:3.97 精巣:3.21 心臓:- 骨格筋:- 食道:- 胃:2.73 腸:3.39 結腸:3.32     肝臓:2.23    肺:3.33 膀胱:2.69 腎臓:- 下垂体:3.34 甲状腺:- 副腎:3.51 膵臓:2.45 乳腺:3.72 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.94 食道:- 胃:- 腸:- 結腸:-     肝臓:1.85        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_010066
Gene ID 13433
Unigene ID Mm.128580
Probe set ID 1435122_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000004099

オーソログ対応遺伝子

ヒト[2]  NM_001130823, NM_001379
ラット [0]  

染色体

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遺伝子ファミリー (Interpro ID)

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Link to Pubmed  (Pubmed ID)

1606615
1628623
3210246
4052092
7537636
7557385
7635139
8026645
8247133
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9449671
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遺伝子オントロジー  (GO ID)

Biological Process

GO:0090116  C-5 methylation of cytosine
GO:0071230  cellular response to amino acid stimulus
GO:0016568  chromatin modification
GO:0006306  DNA methylation
GO:0010424  DNA methylation on cytosine within a CG sequence
GO:0016458  gene silencing
GO:0010216  maintenance of DNA methylation
GO:0008152  metabolic process
GO:0032259  methylation
GO:0051573  negative regulation of histone H3-K9 methylation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0010628  positive regulation of gene expression
GO:0051571  positive regulation of histone H3-K4 methylation
GO:0042127  regulation of cell proliferation
GO:0010468  regulation of gene expression
GO:0006355  regulation of transcription, DNA-dependent
GO:0046498  S-adenosylhomocysteine metabolic process
GO:0046499  S-adenosylmethioninamine metabolic process
GO:0046500  S-adenosylmethionine metabolic process
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005721  centromeric heterochromatin
GO:0005737  cytoplasm
GO:0000792  heterochromatin
GO:0005634  nucleus
GO:0043234  protein complex
GO:0005657  replication fork

Molecular Function

GO:0003824  catalytic activity
GO:0003886  DNA (cytosine-5-)-methyltransferase activity
GO:0051718  DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
GO:0003677  DNA binding
GO:0009008  DNA-methyltransferase activity
GO:0003690  double-stranded DNA binding
GO:0042826  histone deacetylase binding
GO:0046872  metal ion binding
GO:0008327  methyl-CpG binding
GO:0008168  methyltransferase activity
GO:0005515  protein binding
GO:0019904  protein domain specific binding
GO:0003723  RNA binding
GO:0008134  transcription factor binding
GO:0016740  transferase activity
GO:0045322  unmethylated CpG binding
GO:0008270  zinc ion binding