dopamine receptor 3

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Synonym

D3 receptor, D(3) dopamine receptor, D3R, dopamine receptor 3, Drd3

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:3.93

cerebellum:3.95

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.02

spine:3.87

retina:4.02

eye:4.17

artery/aorta:-

vein:3.98

lymphnode:3.77

peripheral blood:-

spleen:3.96

thymus:-

bone marrow:3.83

adipose:3.86

bone:3.99

skin:3.91

CAGE

nodata

RNA-seq

cerebrum:2.72

cerebellum:2.72

brain stem:2.72

corpus callosum/glia:2.72

pineal gland:2.72

peripheral nerve:2.72

spine:2.72

retina:2.72

eye:2.72

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:3.92

placenta:3.86

prostate:3.97

ovary:3.82

testis:4.07

heart:4.16

muscle:3.88

esophagus:-

stomach:4.24

intestine:3.89

colon:-

liver/hepato:4.11

lung:3.72

bladder:3.88

kidney:3.91

pituitary:4.08

thyroid/parathyroid:-

adrenal gland:3.87

pancreas:4.11

breast:3.95

salivary:4.47

CAGE

nodata

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_007877
Gene ID	13490
Unigene ID	-
Probe set ID	1422278_at [Mouse430_2]
Ensembl ID	ENSMUSG00000022705

Orthologous Gene

Human[3]	NM_000796, NM_033663
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR001620	Dopamine D3 receptor
IPR000929	Dopamine receptor
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0046717	acid secretion
GO:0007191	activation of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0050482	arachidonic acid secretion
GO:0048148	behavioral response to cocaine
GO:0006874	cellular calcium ion homeostasis
GO:0032922	circadian regulation of gene expression
GO:0007212	dopamine receptor signaling pathway
GO:0002031	G-protein coupled receptor internalization
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0007195	inhibition of adenylate cyclase activity by dopamine receptor signaling pathway
GO:0007626	locomotory behavior
GO:0050883	musculoskeletal movement, spinal reflex action
GO:0007194	negative regulation of adenylate cyclase activity
GO:0045776	negative regulation of blood pressure
GO:0060160	negative regulation of dopamine receptor signaling pathway
GO:0048715	negative regulation of oligodendrocyte differentiation
GO:0051898	negative regulation of protein kinase B signaling cascade
GO:0050709	negative regulation of protein secretion
GO:0032416	negative regulation of sodium:hydrogen antiporter activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0008284	positive regulation of cell proliferation
GO:0060161	positive regulation of dopamine receptor signaling pathway
GO:0045840	positive regulation of mitosis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0060134	prepulse inhibition
GO:0002016	regulation of blood volume by renin-angiotensin
GO:0030814	regulation of cAMP metabolic process
GO:0045187	regulation of circadian sleep/wake cycle, sleep
GO:0014059	regulation of dopamine secretion
GO:0019216	regulation of lipid metabolic process
GO:0040012	regulation of locomotion
GO:0040014	regulation of multicellular organism growth
GO:0001975	response to amphetamine
GO:0042220	response to cocaine
GO:0042493	response to drug
GO:0045471	response to ethanol
GO:0034776	response to histamine
GO:0043278	response to morphine
GO:0007165	signal transduction
GO:0001963	synaptic transmission, dopaminergic
GO:0008542	visual learning

Cellular Component

GO:0045177	apical part of cell
GO:0042995	cell projection
GO:0030139	endocytic vesicle
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0035240	dopamine binding
GO:0004952	dopamine receptor activity
GO:0001591	dopamine receptor activity, coupled via Gi/Go
GO:0008144	drug binding
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0004871	signal transducer activity

dopamine receptor 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function