Eph receptor B3

Synonym

Ephb3, Tyrosine-protein kinase receptor MDK-5, Cek10, Ephrin type-B receptor 3 precursor, Tyro6, AW456895, Eph receptor B3, MDK5, Developmental kinase 5, Etk2, Mdk5, HEK2, Sek4, SEK-4

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:24.30

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:38.20

spine:-

retina:32.10

eye:38

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:37.60

skin:7.90

GeneChip

cerebrum:6.63

cerebellum:6.39

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.44

spine:6.43

retina:6.87

eye:7.34

artery/aorta:-

vein:7.85

lymphnode:6.08

peripheral blood:-

spleen:6.05

thymus:-

bone marrow:5.88

adipose:6.35

bone:5.89

skin:7.73

CAGE

cerebrum:1.79

cerebellum:-

brain stem:2.03

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:2.17

retina:-

eye:-

artery/aorta:1.59

vein:-

lymphnode:0.71

peripheral blood:-

spleen:0.62

thymus:0.95

bone marrow:-

adipose:-

bone:1.02

skin:4.08

RNA-seq

cerebrum:2.89

cerebellum:2.89

brain stem:2.89

corpus callosum/glia:2.89

pineal gland:2.89

peripheral nerve:2.89

spine:2.89

retina:2.89

eye:2.89

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:13.80

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:65.50

intestine:37

colon:35.20

liver/hepato:-

lung:40.20

bladder:-

kidney:16.10

pituitary:25.80

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:49

salivary:-

GeneChip

uterus:7.54

placenta:6.24

prostate:6.41

ovary:6.48

testis:5.97

heart:6.92

muscle:6.14

esophagus:-

stomach:7.67

intestine:7.27

colon:-

liver/hepato:5.99

lung:7.34

bladder:7.25

kidney:6.32

pituitary:6.70

thyroid/parathyroid:-

adrenal gland:5.81

pancreas:6.49

breast:6.71

salivary:6.86

CAGE

uterus:3.18

placenta:1.96

prostate:1.35

ovary:2.09

testis:0

heart:-

muscle:-

esophagus:-

stomach:3.39

intestine:2.43

colon:2.66

liver/hepato:0.47

lung:3.67

bladder:3.13

kidney:-

pituitary:1.40

thyroid/parathyroid:-

adrenal gland:1.26

pancreas:0.84

breast:2.15

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_010143
Gene ID	13845
Unigene ID	Mm.6972
Probe set ID	1451550_at [Mouse430_2]
Ensembl ID	ENSMUSG00000005958

Orthologous Gene

Human[2]	NM_004443
Rat[1]	NM_001105868

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0007411	axon guidance
GO:0007413	axonal fasciculation
GO:0016477	cell migration
GO:0021952	central nervous system projection neuron axonogenesis
GO:0022038	corpus callosum development
GO:0048546	digestive tract morphogenesis
GO:0048013	ephrin receptor signaling pathway
GO:0007275	multicellular organismal development
GO:0007399	nervous system development
GO:0060021	palate development
GO:0016310	phosphorylation
GO:0051965	positive regulation of synaptogenesis
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0050770	regulation of axonogenesis
GO:0043088	regulation of Cdc42 GTPase activity
GO:0022407	regulation of cell-cell adhesion
GO:0032314	regulation of Rac GTPase activity
GO:0031290	retinal ganglion cell axon guidance
GO:0007165	signal transduction
GO:0034446	substrate adhesion-dependent cell spreading
GO:0048538	thymus development
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0001655	urogenital system development

Cellular Component

GO:0042995	cell projection
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0008046	axon guidance receptor activity
GO:0005003	ephrin receptor activity
GO:0016301	kinase activity
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005005	transmembrane-ephrin receptor activity

IPR001090	Ephrin receptor, ligand binding
IPR003961	Fibronectin, type III
IPR008957	Fibronectin, type III-like fold
IPR008979	Galactose-binding domain-like
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001660	Sterile alpha motif
IPR010993	Sterile alpha motif homology
IPR013761	Sterile alpha motif-type
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR016257	Tyrosine-protein kinase, ephrin receptor
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Eph receptor B3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function