FK506 binding protein 4

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Synonym

AL022792, FK506-binding protein 4, FKBP59, FK506 binding protein 4, HSP-binding immunophilin, AW208983, FKPB52, FKBP52 protein, p59 protein, FKBP-52, HBI, Fkbp4, 52 kDa FK506-binding protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:234.40 cerebellum:55.30 brain stem:63.60 corpus callosum/glia:- pineal gland:257.80 peripheral nerve:152.90 spine:- retina:546.40 eye:212.80 artery/aorta:- vein:- lymphnode:- peripheral blood:172.50 spleen:79 thymus:59.30 bone marrow:179.50 adipose:212.70 bone:150.30 skin:269.20
GeneChip cerebrum:9.01 cerebellum:10.14 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.49 spine:9.89 retina:8.80 eye:8.20 artery/aorta:- vein:8.66 lymphnode:8.84 peripheral blood:- spleen:9.88 thymus:- bone marrow:9.46 adipose:9.81 bone:8.83 skin:8.77
CAGE cerebrum:4.25 cerebellum:- brain stem:4.59 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.51 retina:- eye:- artery/aorta:3.83 vein:- lymphnode:3.38 peripheral blood:- spleen:4.25 thymus:4.16 bone marrow:- adipose:- bone:4.21 skin:3.96
RNA-seq cerebrum:41.18 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:87.20 placenta:248.50 prostate:30.90 ovary:11.50 testis:288.20 heart:223.20 muscle:142 esophagus:- stomach:523.70 intestine:221.80 colon:282     liver/hepato:190.10        lung:381.60    bladder:132.40 kidney:169.20 pituitary:503.80 thyroid/parathyroid:- adrenal gland:- pancreas:140.70 breast:257.90 salivary:486
GeneChip uterus:10.76 placenta:7.96 prostate:10.76 ovary:10.56 testis:11.47 heart:10.73 muscle:10.22 esophagus:- stomach:10.79 intestine:10.94 colon:- liver/hepato:10.55 lung:10.37 bladder:9.58 kidney:10.58 pituitary:9.94 thyroid/parathyroid:- adrenal gland:9.36 pancreas:9.78 breast:9.68 salivary:10.54
CAGE uterus:4.75 placenta:3.62 prostate:5.32 ovary:4.48 testis:6.95 heart:- muscle:- esophagus:- stomach:4.46 intestine:4.71 colon:4.82     liver/hepato:5.26    lung:4.09 bladder:4.10 kidney:- pituitary:4.23 thyroid/parathyroid:- adrenal gland:4.40 pancreas:4.92 breast:4.41 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:29.99 esophagus:- stomach:- intestine:- colon:-     liver/hepato:25.76        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_010219
Gene ID 14228
Unigene ID Mm.12758
Probe set ID 1416362_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030357

Orthologous Gene

Human[4]  NM_002014
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001179  Peptidyl-prolyl cis-trans isomerase, FKBP-type
IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

2592022
7493967
7671812
7693550
8341706
10349636
10512203
10922068
11042159
11076861
11217851
11514552
11751894
12466851
12477932
12520002
12904583
14610273
15489334
15528267
15761153
15782199
15831525
15840001
16141072
16141073
16176985
16873445
17142810
17307907
17571166
17717070
17938211
18554416
18799693
18988805
19073255
19945390
20038533
20427484
20605780
20713718
20796173
21730179
21935478
22416080
22641006
23999428
24049110

Gene Ontology  (GO ID)

Biological Process

GO:0030521  androgen receptor signaling pathway
GO:0006825  copper ion transport
GO:0007566  embryo implantation
GO:0046661  male sex differentiation
GO:0031115  negative regulation of microtubule polymerization
GO:0018208  peptidyl-proline modification
GO:0030850  prostate gland development
GO:0031503  protein complex localization
GO:0006457  protein folding
GO:0000413  protein peptidyl-prolyl isomerization
GO:0048608  reproductive structure development
GO:0006463  steroid hormone receptor complex assembly

Cellular Component

GO:0043025  cell soma
GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0005829  cytosol
GO:0016020  membrane
GO:0005874  microtubule
GO:0005739  mitochondrion
GO:0043005  neuron projection
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0043234  protein complex

Molecular Function

GO:0005524  ATP binding
GO:0032767  copper-dependent protein binding
GO:0005528  FK506 binding
GO:0035259  glucocorticoid receptor binding
GO:0005525  GTP binding
GO:0031072  heat shock protein binding
GO:0016853  isomerase activity
GO:0003755  peptidyl-prolyl cis-trans isomerase activity
GO:0051219  phosphoprotein binding
GO:0005515  protein binding
GO:0048156  tau protein binding