glutamate receptor, ionotropic, kainate 1

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Synonym

glutamate receptor, ionotropic, kainate 1, GluR5, D16Ium24e, A830007B11Rik, Grik1, MGC25101, Glur5, GluR-5, D16Ium24, Glur-5, Glutamate receptor, ionotropic kainate 1 precursor, Glutamate receptor 5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:31.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:189.10 retina:- eye:7.60 artery/aorta:- vein:- lymphnode:- peripheral blood:28.80 spleen:- thymus:- bone marrow:- adipose:- bone:25 skin:15.80
GeneChip cerebrum:4.94 cerebellum:5.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.10 spine:4.70 retina:6.34 eye:3.86 artery/aorta:- vein:3.87 lymphnode:3.51 peripheral blood:- spleen:3.54 thymus:- bone marrow:3.61 adipose:3.63 bone:3.59 skin:3.78
CAGE cerebrum:2.65 cerebellum:- brain stem:2.76 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.51 retina:- eye:- artery/aorta:0 vein:- lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:- bone:0 skin:1.03
RNA-seq cerebrum:2.02 cerebellum:2.02 brain stem:2.02 corpus callosum/glia:2.02 pineal gland:2.02 peripheral nerve:2.02 spine:2.02 retina:2.02 eye:2.02 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:13.80 prostate:- ovary:11.50 testis:66.50 heart:37.20 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:20.10    bladder:66.20 kidney:- pituitary:155 thyroid/parathyroid:- adrenal gland:- pancreas:37.50 breast:- salivary:-
GeneChip uterus:3.65 placenta:3.51 prostate:3.41 ovary:3.56 testis:3.65 heart:3.84 muscle:3.83 esophagus:- stomach:3.60 intestine:3.74 colon:- liver/hepato:3.62 lung:3.65 bladder:3.63 kidney:3.68 pituitary:4.13 thyroid/parathyroid:- adrenal gland:3.62 pancreas:3.74 breast:3.54 salivary:3.80
CAGE uterus:0.44 placenta:0.11 prostate:0.20 ovary:0.13 testis:0 heart:- muscle:- esophagus:- stomach:0 intestine:0.42 colon:0     liver/hepato:0    lung:0.31 bladder:0 kidney:- pituitary:1.86 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:0 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_146072
Gene ID 14805
Unigene ID Mm.51340
Probe set ID 1427676_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000022935

Orthologous Gene

Human[3]  NM_000830, NM_175611
Rat[3]  NM_001111114, NM_001111117, NM_017241

Chromosomal Region

-

Gene Family (Interpro ID)

IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

1310861
1379666
1717158
7523595
7538211
7550346
7959697
8260617
8464923
8700852
8858343
8889548
9016303
9051806
9069287
9244437
9259378
9593973
9619499
9651535
9880586
10349636
10464288
10516295
11042159
11069933
11076861
11144357
11182092
11217851
11985817
12223554
12466851
12466854
12466855
12477932
12777963
12947409
14681479
14715943
14724198
15014126
15358807
15483117
15509753
15513934
15537878
15539395
15673679
15782199
15797031
15805114
15928066
16107646
16141072
16141073
16219388
16354929
16421200
16602821
16948848
17174564
17245443
17428973
17650106
18287559
18358623
18367087
18793656
19208628
19369569
19587272
19679075
19878705
19890917
20081851
20359526
20463214
20513362
20554871
20826661
21734292
22251150
22432643
22534482
22723691
23070814
23076118
23288040
23719165
23786569
24069373
24154525
24760837

Gene Ontology  (GO ID)

Biological Process

GO:0030534  adult behavior
GO:0048266  behavioral response to pain
GO:0006811  ion transport
GO:0035235  ionotropic glutamate receptor signaling pathway
GO:0051899  membrane depolarization
GO:0032229  negative regulation of synaptic transmission, GABAergic
GO:0051967  negative regulation of synaptic transmission, glutamatergic
GO:0007399  nervous system development
GO:0014054  positive regulation of gamma-aminobutyric acid secretion
GO:0032230  positive regulation of synaptic transmission, GABAergic
GO:0060079  regulation of excitatory postsynaptic membrane potential
GO:0060080  regulation of inhibitory postsynaptic membrane potential
GO:0048169  regulation of long-term neuronal synaptic plasticity
GO:0042391  regulation of membrane potential
GO:0048172  regulation of short-term neuronal synaptic plasticity
GO:0035249  synaptic transmission, glutamatergic
GO:0006810  transport

Cellular Component

GO:0030054  cell junction
GO:0043025  cell soma
GO:0030425  dendrite
GO:0016021  integral to membrane
GO:0008328  ionotropic glutamate receptor complex
GO:0032983  kainate selective glutamate receptor complex
GO:0016020  membrane
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0042734  presynaptic membrane
GO:0043235  receptor complex
GO:0045202  synapse
GO:0043195  terminal button

Molecular Function

GO:0008144  drug binding
GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0016595  glutamate binding
GO:0005216  ion channel activity
GO:0004970  ionotropic glutamate receptor activity
GO:0015277  kainate selective glutamate receptor activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004872  receptor activity
GO:0022843  voltage-gated cation channel activity