granzyme B

Synonym

Cytotoxic cell protease 1, Ctla-1, Ctla1, AI553453, CCP1, Gzmb, CTLA-1, granzyme B, Fragmentin-2, CCP-1/C11, Granzyme B(G,H) precursor

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:64.30

cerebellum:18.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:95.50

spine:-

retina:64.30

eye:45.60

artery/aorta:-

vein:-

lymphnode:64.80

peripheral blood:28.80

spleen:223.80

thymus:69.20

bone marrow:-

adipose:-

bone:50.10

skin:110.80

GeneChip

cerebrum:4.83

cerebellum:4.83

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.02

spine:5.20

retina:4.99

eye:5.30

artery/aorta:-

vein:4.92

lymphnode:6.44

peripheral blood:-

spleen:6.60

thymus:-

bone marrow:5.42

adipose:5.19

bone:5.31

skin:4.76

CAGE

cerebrum:0.10

cerebellum:-

brain stem:0.14

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:1.91

vein:-

lymphnode:2.38

peripheral blood:-

spleen:1.49

thymus:0.82

bone marrow:-

adipose:-

bone:0

skin:0

RNA-seq

cerebrum:0.34

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:69

prostate:-

ovary:-

testis:44.30

heart:-

muscle:248.60

esophagus:-

stomach:-

intestine:-

colon:70.50

liver/hepato:9.10

lung:110.50

bladder:-

kidney:48.40

pituitary:387.50

thyroid/parathyroid:112.50

adrenal gland:-

pancreas:37.50

breast:13.10

salivary:54

GeneChip

uterus:7.24

placenta:5.98

prostate:6.20

ovary:4.77

testis:4.93

heart:5.30

muscle:5.26

esophagus:-

stomach:5.22

intestine:7.28

colon:-

liver/hepato:5.08

lung:6.05

bladder:5.04

kidney:4.99

pituitary:4.91

thyroid/parathyroid:-

adrenal gland:5.02

pancreas:5.13

breast:5.90

salivary:5.84

CAGE

uterus:2.07

placenta:3.78

prostate:0.84

ovary:0.25

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:3.04

colon:3.90

liver/hepato:0.47

lung:3.51

bladder:0.68

kidney:-

pituitary:0.29

thyroid/parathyroid:-

adrenal gland:1.87

pancreas:0

breast:1.74

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.68

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_013542
Gene ID	14939
Unigene ID	Mm.148748
Probe set ID	1419060_at [Mouse430_2]
Ensembl ID	ENSMUSG00000015437

Orthologous Gene

Human[1]	NM_004131
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR001254	Peptidase S1/S6, chymotrypsin/Hap
IPR001314	Peptidase S1A, chymotrypsin
IPR009003	Serine/cysteine peptidase, trypsin-like

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0006922	cleavage of lamin
GO:0019835	cytolysis
GO:0008626	induction of apoptosis by granzyme
GO:0008152	metabolic process
GO:0006508	proteolysis
GO:0001913	T cell mediated cytotoxicity

Cellular Component

GO:0044194	cytolytic granule
GO:0005737	cytoplasm
GO:0005769	early endosome
GO:0043231	intracellular membrane-bounded organelle

Molecular Function

GO:0003824	catalytic activity
GO:0016787	hydrolase activity
GO:0008233	peptidase activity
GO:0005515	protein binding
GO:0004252	serine-type endopeptidase activity
GO:0008236	serine-type peptidase activity

granzyme B

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function