5-hydroxytryptamine (serotonin) receptor 2C

Synonym

5-HT2C receptor, Htr1c, Serotonin receptor 2C, 5-hydroxytryptamine (serotonin) receptor 2C, 5ht1c, 5-hydroxytryptamine 2C receptor, 5-HT2cR, 5-HT2C, Htr2c, 5-HT-2C, 5HT1c, 5HT-1C, SR1, 5-HTR2C

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:27.80

cerebellum:36.80

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:141.90

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:6.01

cerebellum:3.88

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:3.91

spine:7.21

retina:3.81

eye:3.91

artery/aorta:-

vein:3.61

lymphnode:3.60

peripheral blood:-

spleen:3.77

thymus:-

bone marrow:3.58

adipose:3.57

bone:3.69

skin:3.69

CAGE

cerebrum:3.76

cerebellum:-

brain stem:4.52

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:4.38

retina:-

eye:-

artery/aorta:0

vein:-

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:-

bone:0

skin:0

RNA-seq

cerebrum:1.72

cerebellum:1.72

brain stem:1.72

corpus callosum/glia:1.72

pineal gland:1.72

peripheral nerve:1.72

spine:1.72

retina:1.72

eye:1.72

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.57

placenta:3.87

prostate:3.63

ovary:3.60

testis:3.73

heart:3.83

muscle:3.79

esophagus:-

stomach:3.58

intestine:3.70

colon:-

liver/hepato:4.12

lung:3.78

bladder:3.70

kidney:3.90

pituitary:3.72

thyroid/parathyroid:-

adrenal gland:3.85

pancreas:3.83

breast:3.72

salivary:3.86

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0

heart:-

muscle:-

esophagus:-

stomach:0

intestine:0.23

colon:0

liver/hepato:0

lung:1.22

bladder:0

kidney:-

pituitary:0.29

thyroid/parathyroid:-

adrenal gland:0

pancreas:0

breast:0

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008312
Gene ID	15560
Unigene ID	Mm.439670
Probe set ID	1450477_at [Mouse430_2]
Ensembl ID	ENSMUSG00000041380

Orthologous Gene

Human[2]	NM_000868
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR000377	5-Hydroxytryptamine 2C receptor
IPR002231	5-Hydroxytryptamine receptor
IPR000276	7TM GPCR, rhodopsin-like
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007208	activation of phospholipase C activity by serotonin receptor signaling pathway
GO:0031583	activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway
GO:0035095	behavioral response to nicotine
GO:0006182	cGMP biosynthetic process
GO:0070371	ERK1 and ERK2 cascade
GO:0007631	feeding behavior
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0048016	inositol phosphate-mediated signaling
GO:0007626	locomotory behavior
GO:0045963	negative regulation of dopamine metabolic process
GO:0040013	negative regulation of locomotion
GO:0006661	phosphatidylinositol biosynthetic process
GO:0014057	positive regulation of acetylcholine secretion
GO:0014054	positive regulation of gamma-aminobutyric acid secretion
GO:0045907	positive regulation of vasoconstriction
GO:0051930	regulation of sensory perception of pain
GO:0051209	release of sequestered calcium ion into cytosol
GO:0042493	response to drug
GO:0007210	serotonin receptor signaling pathway
GO:0007165	signal transduction

Cellular Component

GO:0009986	cell surface
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0008144	drug binding
GO:0004930	G-protein coupled receptor activity
GO:0004435	phosphoinositide phospholipase C activity
GO:0051378	serotonin binding
GO:0004993	serotonin receptor activity
GO:0004871	signal transducer activity

5-hydroxytryptamine (serotonin) receptor 2C

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function