interferon regulatory factor 8

Synonym

interferon regulatory factor 8, Myls, IRF-8, AI893568, ICSBP, Icsbp, Interferon regulatory factor 8, Irf8, Interferon consensus sequence-binding protein, Icsbp1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:17.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:95.50

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:334.80

peripheral blood:158.10

spleen:2133

thymus:276.60

bone marrow:987.30

adipose:-

bone:450.90

skin:15.80

GeneChip

cerebrum:5.22

cerebellum:4.83

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.04

spine:5.59

retina:4.89

eye:6.11

artery/aorta:-

vein:5.69

lymphnode:11.77

peripheral blood:-

spleen:12.06

thymus:-

bone marrow:10.58

adipose:6.59

bone:9.91

skin:5.19

CAGE

cerebrum:0.76

cerebellum:-

brain stem:1.37

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.51

retina:-

eye:-

artery/aorta:2.05

vein:-

lymphnode:5.19

peripheral blood:-

spleen:4.49

thymus:3.41

bone marrow:-

adipose:-

bone:4.31

skin:2.07

RNA-seq

cerebrum:1.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:96.70

prostate:-

ovary:23

testis:22.20

heart:55.80

muscle:35.50

esophagus:-

stomach:-

intestine:221.80

colon:193.80

liver/hepato:72.40

lung:130.50

bladder:132.40

kidney:104.80

pituitary:51.70

thyroid/parathyroid:-

adrenal gland:-

pancreas:9.40

breast:68.60

salivary:54

GeneChip

uterus:8.32

placenta:7.25

prostate:7.03

ovary:7.46

testis:6.51

heart:6.45

muscle:7.51

esophagus:-

stomach:8.24

intestine:9.79

colon:-

liver/hepato:6.67

lung:8.37

bladder:7.54

kidney:6.74

pituitary:5.58

thyroid/parathyroid:-

adrenal gland:6.48

pancreas:6.14

breast:7.66

salivary:7.35

CAGE

uterus:2.81

placenta:2.89

prostate:2.51

ovary:2.07

testis:1.89

heart:-

muscle:-

esophagus:-

stomach:1.75

intestine:3.95

colon:4.60

liver/hepato:2.38

lung:3.34

bladder:2.84

kidney:-

pituitary:1.63

thyroid/parathyroid:-

adrenal gland:2.65

pancreas:2.03

breast:2.22

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.81

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.85

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008320
Gene ID	15900
Unigene ID	Mm.334861
Probe set ID	1416714_at [Mouse430_2]
Ensembl ID	ENSMUSG00000041515

Orthologous Gene

Human[1]	NM_002163
Rat[1]	NM_001008722

Chromosomal Region

Gene Family (Interpro ID)

IPR001346	Interferon regulatory factor
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0071222	cellular response to lipopolysaccharide
GO:0042742	defense response to bacterium
GO:0042832	defense response to protozoan
GO:0006955	immune response
GO:0030099	myeloid cell differentiation
GO:0044130	negative regulation of growth of symbiont in host
GO:0006909	phagocytosis
GO:0032729	positive regulation of interferon-gamma production
GO:0032735	positive regulation of interleukin-12 production
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006355	regulation of transcription, DNA-dependent
GO:0009617	response to bacterium
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005634

nucleus

Molecular Function

GO:0003677	DNA binding
GO:0005515	protein binding
GO:0003700	transcription factor activity

interferon regulatory factor 8

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function