integrin alpha 2

Synonym

Itga2, CD49B, VLA-2 alpha chain, CD49b antigen, Integrin alpha-2 precursor, VLA-2 receptor, alpha 2 subunit, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, integrin alpha 2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:15.20

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:39.50

thymus:-

bone marrow:-

adipose:-

bone:25

skin:-

GeneChip

cerebrum:4.87

cerebellum:4.93

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.73

spine:4.95

retina:4.84

eye:5.13

artery/aorta:-

vein:5.19

lymphnode:5.06

peripheral blood:-

spleen:5.23

thymus:-

bone marrow:5.69

adipose:5.01

bone:5.70

skin:5.39

CAGE

cerebrum:0.10

cerebellum:-

brain stem:0.07

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.32

retina:-

eye:-

artery/aorta:1.40

vein:-

lymphnode:2.91

peripheral blood:-

spleen:1.41

thymus:0.67

bone marrow:-

adipose:-

bone:2.88

skin:3.37

RNA-seq

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:13.80

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.26

placenta:6.25

prostate:4.92

ovary:5.05

testis:6.93

heart:5.38

muscle:5.21

esophagus:-

stomach:5.22

intestine:6.14

colon:-

liver/hepato:5.18

lung:5.66

bladder:5.29

kidney:5.07

pituitary:5.03

thyroid/parathyroid:-

adrenal gland:5.05

pancreas:5.10

breast:5.19

salivary:5.11

CAGE

uterus:3.27

placenta:3.59

prostate:0.93

ovary:2.61

testis:0

heart:-

muscle:-

esophagus:-

stomach:2.16

intestine:3.01

colon:3.09

liver/hepato:0.26

lung:3.39

bladder:2.92

kidney:-

pituitary:0.86

thyroid/parathyroid:-

adrenal gland:1.52

pancreas:0

breast:1.26

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:0.91

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008396
Gene ID	16398
Unigene ID	Mm.5007
Probe set ID	1450501_at [Mouse430_2]
Ensembl ID	ENSMUSG00000015533

Orthologous Gene

Human[1]	NM_002203
Rat[1]	NM_002203

Chromosomal Region

Gene Family (Interpro ID)

IPR013517	FG-GAP
IPR013519	Integrin alpha beta-propellor

Gene Ontology (GO ID)

Biological Process

GO:0007155	cell adhesion
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain
GO:0045184	establishment of protein localization
GO:0006971	hypotonic response
GO:0007229	integrin-mediated signaling pathway
GO:0010694	positive regulation of alkaline phosphatase activity
GO:0045785	positive regulation of cell adhesion
GO:0031346	positive regulation of cell projection organization
GO:0033343	positive regulation of collagen binding
GO:0032967	positive regulation of collagen biosynthetic process
GO:0043388	positive regulation of DNA binding
GO:0010634	positive regulation of epithelial cell migration
GO:0050729	positive regulation of inflammatory response
GO:0002687	positive regulation of leukocyte migration
GO:0060100	positive regulation of phagocytosis, engulfment
GO:0050927	positive regulation of positive chemotaxis
GO:0014911	positive regulation of smooth muscle cell migration
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0045987	positive regulation of smooth muscle contraction
GO:0045727	positive regulation of translation
GO:0051971	positive regulation of transmission of nerve impulse
GO:0043589	skin morphogenesis
GO:0001894	tissue homeostasis

Cellular Component

GO:0030424	axon
GO:0045178	basal part of cell
GO:0009279	cell outer membrane
GO:0042995	cell projection
GO:0009986	cell surface
GO:0009897	external side of plasma membrane
GO:0005925	focal adhesion
GO:0016021	integral to membrane
GO:0008305	integrin complex
GO:0016020	membrane
GO:0043679	nerve terminal
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0005178	integrin binding
GO:0043236	laminin binding
GO:0046872	metal ion binding
GO:0032403	protein complex binding
GO:0046982	protein heterodimerization activity

integrin alpha 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function