paired-like homeodomain transcription factor 2

Synonym

Rgs, solurshin, Munc30, Brx1a, Pitx2b, paired-like homeodomain transcription factor 2, 9430085M16Rik, Brx1b, ALL1-responsive protein ARP1, Orthodenticle-like homeobox 2, Pituitary homeobox 2, Brx1, Pitx2a, Pitx2c, Otlx2, BRX1 homeoprotein, Solurshin, Rieg, Pitx2, Ptx2

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:8.70

cerebellum:-

brain stem:63.60

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:60.80

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:12.50

skin:31.70

GeneChip

cerebrum:4.85

cerebellum:4.77

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:4.66

spine:4.95

retina:4.82

eye:5.56

artery/aorta:-

vein:10.58

lymphnode:4.68

peripheral blood:-

spleen:4.36

thymus:-

bone marrow:4.44

adipose:5.74

bone:4.73

skin:5.09

CAGE

cerebrum:0

cerebellum:-

brain stem:0.76

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.55

retina:-

eye:-

artery/aorta:0.25

vein:-

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:-

bone:0.63

skin:1.42

RNA-seq

cerebrum:1.04

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:27.60

prostate:-

ovary:23

testis:14.80

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:36.20

lung:-

bladder:132.40

kidney:-

pituitary:258.30

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.55

placenta:5.97

prostate:4.96

ovary:4.58

testis:6.18

heart:5.17

muscle:6.16

esophagus:-

stomach:8.46

intestine:5.79

colon:-

liver/hepato:5.06

lung:4.55

bladder:8.13

kidney:5.33

pituitary:10.01

thyroid/parathyroid:-

adrenal gland:4.47

pancreas:5.21

breast:6.23

salivary:5.05

CAGE

uterus:0

placenta:1.65

prostate:0

ovary:0

testis:0

heart:-

muscle:-

esophagus:-

stomach:0.67

intestine:2.76

colon:2.50

liver/hepato:0.47

lung:0

bladder:3.63

kidney:-

pituitary:4.48

thyroid/parathyroid:-

adrenal gland:0

pancreas:0

breast:0

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.47

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001042502
Gene ID	18741
Unigene ID	Mm.246804
Probe set ID	1450482_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000028023

Orthologous Gene

Human[3]	NM_000325, NM_001204397, NM_001204398, NM_001204399, NM_153426, NM_153427
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

Gene Ontology (GO ID)

Biological Process

GO:0009653	anatomical structure morphogenesis
GO:0055009	atrial cardiac muscle tissue morphogenesis
GO:0003171	atrioventricular valve development
GO:0043010	camera-type eye development
GO:0055007	cardiac muscle cell differentiation
GO:0048738	cardiac muscle tissue development
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis
GO:0007368	determination of left/right symmetry
GO:0055123	digestive system development
GO:0031076	embryonic camera-type eye development
GO:0048557	embryonic digestive tract morphogenesis
GO:0035116	embryonic hindlimb morphogenesis
GO:0002074	extraocular skeletal muscle development
GO:0007507	heart development
GO:0021855	hypothalamus cell migration
GO:0001701	in utero embryonic development
GO:0060460	left lung morphogenesis
GO:0070986	left/right axis specification
GO:0030324	lung development
GO:0007275	multicellular organismal development
GO:0007520	myoblast fusion
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001764	neuron migration
GO:0042476	odontogenesis
GO:0009887	organ morphogenesis
GO:0001569	patterning of blood vessels
GO:0021983	pituitary gland development
GO:0043388	positive regulation of DNA binding
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0003350	pulmonary myocardium development
GO:0060577	pulmonary vein morphogenesis
GO:0030334	regulation of cell migration
GO:0042127	regulation of cell proliferation
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0007519	skeletal muscle tissue development
GO:0048536	spleen development
GO:0021763	subthalamic nucleus development
GO:0060578	superior vena cava morphogenesis
GO:0001570	vasculogenesis
GO:0055015	ventricular cardiac muscle cell development
GO:0060412	ventricular septum morphogenesis
GO:0016055	Wnt receptor signaling pathway

Cellular Component

GO:0005737	cytoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0003682	chromatin binding
GO:0031490	chromatin DNA binding
GO:0003677	DNA binding
GO:0051219	phosphoprotein binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity
GO:0008134	transcription factor binding

paired-like homeodomain transcription factor 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function