protein kinase C, beta

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Synonym

A130082F03Rik, PKC-B, Prkcb1, Protein kinase C beta type, PKC-Beta, Pkcb, Prkcb, PKC-beta, protein kinase C, beta 1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:184.10

cerebellum:92.10

brain stem:127.10

corpus callosum/glia:-

pineal gland:515.60

peripheral nerve:76.40

spine:-

retina:32.10

eye:83.60

artery/aorta:-

vein:-

lymphnode:162

peripheral blood:86.30

spleen:158

thymus:217.40

bone marrow:12.80

adipose:-

bone:12.50

skin:-

GeneChip

cerebrum:10.73

cerebellum:9.97

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.98

spine:7.98

retina:6.70

eye:7.32

artery/aorta:-

vein:6.40

lymphnode:9.33

peripheral blood:-

spleen:9.94

thymus:-

bone marrow:8.46

adipose:5.44

bone:8.40

skin:6.13

CAGE

cerebrum:5.57

cerebellum:-

brain stem:5.08

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:5.04

retina:-

eye:-

artery/aorta:2.88

vein:-

lymphnode:5.10

peripheral blood:-

spleen:4.78

thymus:5.67

bone marrow:-

adipose:-

bone:4.65

skin:2.95

RNA-seq

cerebrum:28.02

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:36.20

lung:20.10

bladder:-

kidney:-

pituitary:51.70

thyroid/parathyroid:-

adrenal gland:-

pancreas:18.80

breast:22.90

salivary:-

GeneChip

uterus:6.47

placenta:4.60

prostate:5.37

ovary:5.61

testis:4.93

heart:4.90

muscle:5.37

esophagus:-

stomach:5.15

intestine:4.98

colon:-

liver/hepato:4.79

lung:5.17

bladder:8.84

kidney:4.66

pituitary:6.44

thyroid/parathyroid:-

adrenal gland:7.16

pancreas:6.96

breast:6.02

salivary:5.13

CAGE

uterus:3.07

placenta:0.90

prostate:2.76

ovary:2.65

testis:1.80

heart:-

muscle:-

esophagus:-

stomach:2.04

intestine:1.65

colon:2.68

liver/hepato:2.13

lung:3.57

bladder:4.88

kidney:-

pituitary:3.48

thyroid/parathyroid:-

adrenal gland:3.30

pancreas:2.66

breast:2.91

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.44

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.93

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008855
Gene ID	18751
Unigene ID	Mm.207496
Probe set ID	1423478_at [Mouse430_2]
Ensembl ID	ENSMUSG00000052889

Orthologous Gene

Human[3]	NM_002738, NM_212535
Rat[3]	NM_001172305, NM_012713

Chromosomal Region

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0042113	B cell activation
GO:0050853	B cell receptor signaling pathway
GO:0006816	calcium ion transport
GO:0006874	cellular calcium ion homeostasis
GO:0071322	cellular response to carbohydrate stimulus
GO:0016568	chromatin modification
GO:0010829	negative regulation of glucose transport
GO:0046627	negative regulation of insulin receptor signaling pathway
GO:0016310	phosphorylation
GO:0045766	positive regulation of angiogenesis
GO:0050861	positive regulation of B cell receptor signaling pathway
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0006468	protein amino acid phosphorylation
GO:0014059	regulation of dopamine secretion
GO:0040008	regulation of growth
GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-dependent
GO:0042493	response to drug
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0031526	brush border membrane
GO:0005813	centrosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0050681	androgen receptor binding
GO:0005524	ATP binding
GO:0005246	calcium channel regulator activity
GO:0003682	chromatin binding
GO:0042393	histone binding
GO:0016301	kinase activity
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004697	protein kinase C activity
GO:0005080	protein kinase C binding
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0008270	zinc ion binding

IPR000961	AGC-kinase, C-terminal
IPR000008	C2 calcium-dependent membrane targeting
IPR008973	C2 calcium/lipid-binding domain, CaLB
IPR018029	C2 membrane targeting protein
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

protein kinase C, beta

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function