paired-like homeobox 2b

Synonym

Phox2b, NBPhox, Neuroblastoma Phox, Paired-like homeobox 2B, Dilp1, Pmx2b, PHOX2B homeodomain protein, GENA 269, paired-like homeobox 2b, Paired mesoderm homeobox protein 2B

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.70

cerebellum:-

brain stem:158.90

corpus callosum/glia:-

pineal gland:-

peripheral nerve:363.10

spine:-

retina:-

eye:-

artery/aorta:84.40

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.29

cerebellum:5.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.32

spine:5.55

retina:5.70

eye:5.56

artery/aorta:-

vein:5.27

lymphnode:4.90

peripheral blood:-

spleen:5.10

thymus:-

bone marrow:5.24

adipose:5.31

bone:5.26

skin:5.05

CAGE

cerebrum:0

cerebellum:-

brain stem:0.89

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0.36

vein:-

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:-

bone:0

skin:0

RNA-seq

cerebrum:0.80

cerebellum:0.80

brain stem:0.80

corpus callosum/glia:0.80

pineal gland:0.80

peripheral nerve:0.80

spine:0.80

retina:0.80

eye:0.80

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:30.90

ovary:-

testis:-

heart:-

muscle:35.50

esophagus:-

stomach:163.60

intestine:-

colon:17.60

liver/hepato:-

lung:10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:1697.80

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.12

placenta:5.25

prostate:5.21

ovary:4.89

testis:5.72

heart:5.68

muscle:5.46

esophagus:-

stomach:5.43

intestine:5.34

colon:-

liver/hepato:5.68

lung:5.01

bladder:5.12

kidney:5.37

pituitary:5.30

thyroid/parathyroid:-

adrenal gland:6.25

pancreas:5.83

breast:5.38

salivary:5.27

CAGE

uterus:0

placenta:0

prostate:1.46

ovary:0

testis:0

heart:-

muscle:-

esophagus:-

stomach:1.07

intestine:1.14

colon:0.57

liver/hepato:0

lung:0

bladder:1.41

kidney:-

pituitary:0

thyroid/parathyroid:-

adrenal gland:3.11

pancreas:0

breast:0

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_008888
Gene ID	18935
Unigene ID	Mm.62505
Probe set ID	1422232_at [Mouse430_2]
Ensembl ID	ENSMUSG00000012520

Orthologous Gene

Human[1]	NM_003924
Rat[1]	NM_003924

Chromosomal Region

Gene Family (Interpro ID)

IPR001356	Homeobox
IPR009057	Homeodomain-like
IPR012287	Homeodomain-related

Gene Ontology (GO ID)

Biological Process

GO:0048483	autonomic nervous system development
GO:0048468	cell development
GO:0021533	cell differentiation in hindbrain
GO:0048894	efferent axon development in a lateral line nerve
GO:0048484	enteric nervous system development
GO:0010001	glial cell differentiation
GO:0021934	hindbrain tangential cell migration
GO:0048839	inner ear development
GO:0007275	multicellular organismal development
GO:0008285	negative regulation of cell proliferation
GO:0045665	negative regulation of neuron differentiation
GO:0030182	neuron differentiation
GO:0001764	neuron migration
GO:0003357	noradrenergic neuron differentiation
GO:0048486	parasympathetic nervous system development
GO:0045666	positive regulation of neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0002087	regulation of respiratory gaseous exchange by neurological system process
GO:0006355	regulation of transcription, DNA-dependent
GO:0060541	respiratory system development
GO:0048485	sympathetic nervous system development

Cellular Component

GO:0000790	nuclear chromatin
GO:0005634	nucleus

Molecular Function

GO:0003677	DNA binding
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity

paired-like homeobox 2b

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function