PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)

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Synonym

Pif1, 4631410M14, expressed sequence AI449441, AI449441

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19.10 cerebellum:165.80 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:64.30 eye:22.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:52.70 thymus:177.80 bone marrow:- adipose:- bone:12.50 skin:87.10
GeneChip nodata
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:- lymphnode:1.28 peripheral blood:- spleen:2.76 thymus:2.54 bone marrow:- adipose:- bone:2.37 skin:1.09
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:34.50 testis:14.80 heart:37.20 muscle:- esophagus:- stomach:196.40 intestine:- colon:17.60     liver/hepato:-        lung:50.20    bladder:- kidney:- pituitary:25.80 thyroid/parathyroid:- adrenal gland:- pancreas:- breast:42.40 salivary:-
GeneChip nodata
CAGE uterus:0.74 placenta:0.70 prostate:0.37 ovary:0.88 testis:0 heart:- muscle:- esophagus:- stomach:1.07 intestine:1.43 colon:1.58     liver/hepato:0    lung:0.31 bladder:0 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:1.23 salivary:-
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_172453
Gene ID 208084
Unigene ID Mm.211032
Probe set ID -
Ensembl ID ENSMUSG00000041064

Orthologous Gene

Human[1]  NM_025049
Rat[1]  NM_001044253

Chromosomal Region

9C  [65,434,967  -  65,443,774]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10349636
11042159
11076861
11217851
12466851
12477932
14610273
15782199
16107646
16141072
16141073
17130244
18799693
21267068
21677750
21945094
23275553

Gene Ontology  (GO ID)

Biological Process

GO:0006281  DNA repair
GO:0051974  negative regulation of telomerase activity
GO:0032204  regulation of telomere maintenance
GO:0000723  telomere maintenance

Cellular Component

GO:0000784  nuclear chromosome, telomeric region
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0043141  ATP-dependent 5'-3' DNA helicase activity
GO:0033682  ATP-dependent 5'-3' DNA/RNA helicase activity
GO:0003677  DNA binding
GO:0003678  DNA helicase activity
GO:0004386  helicase activity
GO:0016787  hydrolase activity
GO:0000287  magnesium ion binding
GO:0000166  nucleotide binding
GO:0017116  single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0042162  telomeric DNA binding