ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog (yeast)

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Synonym

Ubiquitin-conjugating enzyme E2 D1, Ubiquitin-conjugating enzyme E2-17 kDa 1, UBCH5, Ubiquitin carrier protein D1, Ubiquitin-protein ligase D1, E2(17)KB 1, MGC28550, Ube2d1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:39.90 cerebellum:73.70 brain stem:222.50 corpus callosum/glia:- pineal gland:- peripheral nerve:38.20 spine:331 retina:96.40 eye:38 artery/aorta:- vein:- lymphnode:75.60 peripheral blood:14.40 spleen:65.80 thymus:98.80 bone marrow:51.30 adipose:- bone:25 skin:39.60
GeneChip cerebrum:8.49 cerebellum:8.48 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:8.81 spine:8.76 retina:5.31 eye:5.23 artery/aorta:- vein:7.59 lymphnode:8.62 peripheral blood:- spleen:8.45 thymus:- bone marrow:7.64 adipose:7.95 bone:7.38 skin:8.23
CAGE cerebrum:4.46 cerebellum:- brain stem:4.79 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.95 retina:- eye:- artery/aorta:3.53 vein:- lymphnode:4.69 peripheral blood:- spleen:2.92 thymus:3.95 bone marrow:- adipose:- bone:4.47 skin:4.87
RNA-seq cerebrum:13.41 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:13.80 prostate:30.90 ovary:- testis:7.40 heart:55.80 muscle:142 esophagus:- stomach:65.50 intestine:- colon:88.10     liver/hepato:-        lung:30.10    bladder:- kidney:32.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:28.10 breast:42.40 salivary:-
GeneChip uterus:8.66 placenta:6.68 prostate:8.18 ovary:8.18 testis:5.34 heart:8.83 muscle:11.41 esophagus:- stomach:7.63 intestine:7.70 colon:- liver/hepato:6.43 lung:7.91 bladder:8.69 kidney:7.65 pituitary:8.47 thyroid/parathyroid:- adrenal gland:6.88 pancreas:5.58 breast:9.13 salivary:6.30
CAGE uterus:4.02 placenta:2.71 prostate:2.85 ovary:3.75 testis:3.03 heart:- muscle:- esophagus:- stomach:4.20 intestine:2.86 colon:3.07     liver/hepato:2.82    lung:3.41 bladder:4.17 kidney:- pituitary:3.78 thyroid/parathyroid:- adrenal gland:3.00 pancreas:3.04 breast:2.90 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:45.52 esophagus:- stomach:- intestine:- colon:-     liver/hepato:2.43        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_145420
Gene ID 216080
Unigene ID Mm.270530
Probe set ID 1424062_at  [Mouse430_2]
Ensembl ID ENSMUSG00000019927

Orthologous Gene

Human[2]  NM_001204880, NM_003338
Rat[1]  NM_001108530, NM_003338

Chromosomal Region

-

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
12466851
12477932
14610273
14980219
15139022
15489334
15782199
16141072
16141073
16602821
18511420
18515077
18799693
21267068
21677750
22334701
22797923
23095357
23509263
23871831

Gene Ontology  (GO ID)

Biological Process

GO:0008152  metabolic process
GO:0031398  positive regulation of protein ubiquitination
GO:0070936  protein K48-linked ubiquitination
GO:0000209  protein polyubiquitination
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0016881  acid-amino acid ligase activity
GO:0005524  ATP binding
GO:0016874  ligase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004842  ubiquitin-protein ligase activity