tissue inhibitor of metalloproteinase 1

Synonym

EPA, Timp-1, MGC7143, Clgi, TPA-induced protein, Timp1, TPA-S1, Collagenase inhibitor 16C8 fibroblast, tissue inhibitor of metalloproteinase 1, Tissue inhibitor of metalloproteinases, TIMP-1, Metalloproteinase inhibitor 1 precursor, Timp, Erythroid potentiating activity

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:57.30

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:26.30

thymus:19.80

bone marrow:-

adipose:-

bone:187.90

skin:-

GeneChip

cerebrum:5.52

cerebellum:5.52

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:6.24

spine:5.73

retina:5.50

eye:6.66

artery/aorta:-

vein:9.64

lymphnode:7.27

peripheral blood:-

spleen:6.49

thymus:-

bone marrow:5.70

adipose:6.55

bone:7.94

skin:5.50

CAGE

cerebrum:0.54

cerebellum:-

brain stem:0.44

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:0.83

retina:-

eye:-

artery/aorta:1.80

vein:-

lymphnode:2.67

peripheral blood:-

spleen:1.41

thymus:1.06

bone marrow:-

adipose:-

bone:1.84

skin:1.42

RNA-seq

cerebrum:1.24

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:43.60

placenta:13.80

prostate:-

ovary:23

testis:73.90

heart:18.60

muscle:284.10

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:37.50

breast:107.70

salivary:-

GeneChip

uterus:7.47

placenta:7.11

prostate:7

ovary:10.06

testis:5.93

heart:6.94

muscle:5.74

esophagus:-

stomach:5.95

intestine:5.90

colon:-

liver/hepato:6.18

lung:7.64

bladder:7.09

kidney:5.55

pituitary:6.56

thyroid/parathyroid:-

adrenal gland:7.72

pancreas:5.83

breast:7.05

salivary:9.10

CAGE

uterus:2.50

placenta:3.01

prostate:1.09

ovary:4.57

testis:1.48

heart:-

muscle:-

esophagus:-

stomach:1.75

intestine:0.72

colon:0.23

liver/hepato:0.47

lung:1.96

bladder:2.12

kidney:-

pituitary:2.10

thyroid/parathyroid:-

adrenal gland:3.67

pancreas:0.84

breast:2.58

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.85

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:0

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001044384
Gene ID	21857
Unigene ID	Mm.8245
Probe set ID	1460227_at [Mouse430_2]
Ensembl ID	ENSMUSG00000001131

Orthologous Gene

Human[1]	NM_003254
Rat [0]

Chromosomal Region

Gene Family (Interpro ID)

IPR001134	Netrin domain
IPR001820	Proteinase inhibitor I35, tissue inhibitor of metalloproteinase
IPR008993	TIMP-like, OB-fold

GO:0001775	cell activation
GO:0043249	erythrocyte maturation
GO:0043066	negative regulation of apoptosis
GO:0043086	negative regulation of catalytic activity
GO:0051045	negative regulation of membrane protein ectodomain proteolysis
GO:0010466	negative regulation of peptidase activity

GO:0005604	basement membrane
GO:0031012	extracellular matrix
GO:0005576	extracellular region
GO:0005578	proteinaceous extracellular matrix

GO:0004857	enzyme inhibitor activity
GO:0046872	metal ion binding
GO:0008191	metalloendopeptidase inhibitor activity
GO:0030414	peptidase inhibitor activity
GO:0002020	protease binding

tissue inhibitor of metalloproteinase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function