IKAROS family zinc finger 1

Synonym

5832432G11Rik, DNA-binding protein Ikaros, Znfn1a1, mKIAA4227, IKAROS family zinc finger 1, IKAROS family zinc finger protein 1, KIAA4227, Lyf1, hlk-1, Ikaros, Zfpn1a1, Lymphoid transcription factor LyF-1, LyF-1, Ikzf1

normal 40 tissues
developmental tissues and primary cells（FANTOM5 CAGE）

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:5.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:19.10

spine:47.30

retina:-

eye:-

artery/aorta:168.80

vein:-

lymphnode:140.40

peripheral blood:158.10

spleen:316

thymus:375.40

bone marrow:333.40

adipose:-

bone:87.70

skin:31.70

GeneChip

cerebrum:5.36

cerebellum:5.34

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:5.07

spine:5.79

retina:5.55

eye:5.59

artery/aorta:-

vein:5.33

lymphnode:8.90

peripheral blood:-

spleen:8.28

thymus:-

bone marrow:8.31

adipose:5.76

bone:7.10

skin:5.09

CAGE

cerebrum:0.79

cerebellum:-

brain stem:1.11

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:1.63

retina:-

eye:-

artery/aorta:2.80

vein:-

lymphnode:5.61

peripheral blood:-

spleen:5.21

thymus:5.59

bone marrow:-

adipose:-

bone:5.16

skin:2.11

RNA-seq

cerebrum:1.12

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:55.20

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:65.50

intestine:-

colon:-

liver/hepato:27.20

lung:10

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:45.70

salivary:54

GeneChip

uterus:5.64

placenta:5.60

prostate:5.29

ovary:5.29

testis:5.74

heart:5.54

muscle:5.53

esophagus:-

stomach:5.52

intestine:5.44

colon:-

liver/hepato:5.68

lung:5.56

bladder:5.54

kidney:5.75

pituitary:5.57

thyroid/parathyroid:-

adrenal gland:5

pancreas:5.83

breast:6.17

salivary:5.38

CAGE

uterus:2.03

placenta:1.37

prostate:1.41

ovary:1.94

testis:0.45

heart:-

muscle:-

esophagus:-

stomach:0

intestine:1.65

colon:2.58

liver/hepato:1.85

lung:3.70

bladder:1.92

kidney:-

pituitary:1.40

thyroid/parathyroid:-

adrenal gland:2.37

pancreas:1.61

breast:3.57

salivary:-

RNA-seq

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:1.76

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:1.70

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

IDs

Refseq ID	NM_001025597
Gene ID	22778
Unigene ID	Mm.103545
Probe set ID	1421303_at [Mouse430_2]
Ensembl ID	ENSMUSG00000018654

Orthologous Gene

Human[4]	NM_001220765, NM_001220766, NM_001220767, NM_001220768, NM_001220769, NM_001220770, NM_001220771, NM_001220772, NM_001220773, NM_001220774, NM_001220775, NM_001220776, NM_006060
Rat[1]	NM_001107237, NM_001220766, NM_001220767, NM_001220768, NM_001220769, NM_001220770, NM_001220771, NM_001220772, NM_001220773, NM_001220774, NM_001220775, NM_001220776, NM_006060

Chromosomal Region

Gene Family (Interpro ID)

IPR015880	Zinc finger, C2H2-like
IPR007087	Zinc finger, C2H2-type

Gene Ontology (GO ID)

Biological Process

GO:0030183	B cell differentiation
GO:0007049	cell cycle
GO:0016568	chromatin modification
GO:0030900	forebrain development
GO:0048732	gland development
GO:0030097	hemopoiesis
GO:0048535	lymph node development
GO:0007275	multicellular organismal development
GO:0001779	natural killer cell differentiation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0048541	Peyer's patch development
GO:0040018	positive regulation of multicellular organism growth
GO:0045660	positive regulation of neutrophil differentiation
GO:0051138	positive regulation of NK T cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006355	regulation of transcription, DNA-dependent
GO:0060041	retina development in camera-type eye
GO:0030217	T cell differentiation
GO:0048538	thymus development
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005721	centromeric heterochromatin
GO:0005737	cytoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0046872	metal ion binding
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0043565	sequence-specific DNA binding
GO:0003700	transcription factor activity

IKAROS family zinc finger 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function