hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit

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Synonym

4930479F15Rik, Hadhb, Mtpb, TP-beta

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:64.30 cerebellum:92.10 brain stem:63.60 corpus callosum/glia:- pineal gland:- peripheral nerve:76.40 spine:47.30 retina:64.30 eye:174.80 artery/aorta:506.30 vein:- lymphnode:10.80 peripheral blood:28.80 spleen:52.70 thymus:79 bone marrow:115.40 adipose:- bone:37.60 skin:134.60
GeneChip cerebrum:8.68 cerebellum:9.06 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:10.09 spine:9.33 retina:10.12 eye:10.11 artery/aorta:- vein:9.45 lymphnode:9.99 peripheral blood:- spleen:9.04 thymus:- bone marrow:9.43 adipose:11.18 bone:9.73 skin:10.40
CAGE nodata
RNA-seq cerebrum:18.92 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:55.20 prostate:123.50 ovary:91.90 testis:133 heart:409.20 muscle:319.60 esophagus:- stomach:65.50 intestine:37 colon:158.60     liver/hepato:144.80        lung:80.30    bladder:463.30 kidney:233.70 pituitary:193.80 thyroid/parathyroid:224.90 adrenal gland:- pancreas:28.10 breast:120.80 salivary:216
GeneChip uterus:9.39 placenta:9.64 prostate:10.33 ovary:10.29 testis:9.35 heart:11.89 muscle:11.17 esophagus:- stomach:10.50 intestine:10.13 colon:- liver/hepato:10.78 lung:9.54 bladder:10.46 kidney:10.09 pituitary:9.99 thyroid/parathyroid:- adrenal gland:11.61 pancreas:9.29 breast:10.87 salivary:10.84
CAGE nodata
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:61.60 esophagus:- stomach:- intestine:- colon:-     liver/hepato:43.68        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_145558
Gene ID 231086
Unigene ID Mm.291463
Probe set ID 1437172_x_at  [Mouse430_2]
Ensembl ID ENSMUSG00000059447

Orthologous Gene

Human[1]  NM_000183
Rat [0]  

Chromosomal Region

-

Gene Family (Interpro ID)

IPR002155  Thiolase

Link to Pubmed  (Pubmed ID)

8889548
10349636
10922068
11042159
11076861
11116090
11217851
11390422
12466851
12477932
12865426
12904583
14610273
14651853
14681479
15240869
15489334
15782199
16141072
16141073
16916647
17116638
18614015
18799693
21267068
21565611
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0006635  fatty acid beta-oxidation
GO:0006631  fatty acid metabolic process
GO:0006629  lipid metabolic process
GO:0008152  metabolic process
GO:0055114  oxidation reduction

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0016507  fatty acid beta-oxidation multienzyme complex
GO:0016020  membrane
GO:0005743  mitochondrial inner membrane
GO:0042645  mitochondrial nucleoid
GO:0005741  mitochondrial outer membrane
GO:0005739  mitochondrion

Molecular Function

GO:0003857  3-hydroxyacyl-CoA dehydrogenase activity
GO:0003988  acetyl-CoA C-acyltransferase activity
GO:0000062  acyl-CoA binding
GO:0003824  catalytic activity
GO:0004300  enoyl-CoA hydratase activity
GO:0016509  long-chain-3-hydroxyacyl-CoA dehydrogenase activity
GO:0016508  long-chain-enoyl-CoA hydratase activity
GO:0051287  NAD or NADH binding
GO:0032403  protein complex binding
GO:0016740  transferase activity
GO:0016746  transferase activity, transferring acyl groups
GO:0016747  transferase activity, transferring acyl groups other than amino-acyl groups