ArfGAP with dual PH domains 1

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Synonym

Centa1, 4930431P11Rik, centaurin, alpha 1, p42IP4, GC1L

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:85.10 cerebellum:92.10 brain stem:254.20 corpus callosum/glia:- pineal gland:- peripheral nerve:57.30 spine:283.70 retina:- eye:7.60 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:425.40 bone:25 skin:7.90
GeneChip nodata
CAGE cerebrum:4.16 cerebellum:- brain stem:4.52 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:4.53 retina:- eye:- artery/aorta:1.53 vein:- lymphnode:2.67 peripheral blood:- spleen:2.42 thymus:1.50 bone marrow:- adipose:- bone:2.97 skin:1.86
RNA-seq cerebrum:54.61 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:41.40 prostate:- ovary:11.50 testis:36.90 heart:- muscle:- esophagus:- stomach:- intestine:110.90 colon:17.60     liver/hepato:9.10        lung:-    bladder:66.20 kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:3.30 salivary:-
GeneChip nodata
CAGE uterus:1.69 placenta:2.40 prostate:1.23 ovary:1.14 testis:3.11 heart:- muscle:- esophagus:- stomach:2.52 intestine:4.60 colon:4.73     liver/hepato:0.78    lung:1.91 bladder:3.33 kidney:- pituitary:1.11 thyroid/parathyroid:- adrenal gland:1.72 pancreas:1.30 breast:1.47 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:1.28 esophagus:- stomach:- intestine:- colon:-     liver/hepato:1.63        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_172723
Gene ID 231821
Unigene ID Mm.297819
Probe set ID -
Ensembl ID ENSMUSG00000056413

Orthologous Gene

Human[2]  NM_006869
Rat [0]  

Chromosomal Region

5G2  [139,747,830  -  139,801,576]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11125038
11217851
12466851
12477932
14610273
16141072
16141073
16602821
18799693
21267068
21677750

Gene Ontology  (GO ID)

Biological Process

GO:0043087  regulation of GTPase activity

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0008060  ARF GTPase activator activity
GO:0046872  metal ion binding
GO:0005547  phosphatidylinositol-3,4,5-trisphosphate binding