sulfatase 1

 jump to detail

Synonym

MSulf-1, AW121680, Extracellular sulfatase Sulf-1 precursor, mKIAA1077, sulfatase 1, Sulf1, AI467640

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:3.46 cerebellum:- brain stem:2.76 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:2.40 retina:- eye:- artery/aorta:4.92 vein:- lymphnode:4.63 peripheral blood:- spleen:2.04 thymus:2.57 bone marrow:- adipose:- bone:2.29 skin:2.97
RNA-seq cerebrum:3.15 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:3.72 placenta:2.06 prostate:3.42 ovary:3.22 testis:2.12 heart:- muscle:- esophagus:- stomach:1.75 intestine:1.92 colon:2.03     liver/hepato:1.12    lung:3.71 bladder:3.95 kidney:- pituitary:3.57 thyroid/parathyroid:- adrenal gland:3.04 pancreas:2.45 breast:1.99 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:2.24 esophagus:- stomach:- intestine:- colon:-     liver/hepato:0        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_172294
Gene ID 240725
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000016918

Orthologous Gene

Human[12]  NM_001128204, NM_001128205, NM_001128206, NM_015170
Rat[1]  NM_134378, NM_001128205, NM_001128206, NM_015170

Chromosomal Region

1A3  [12,708,626  -  12,850,452]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8889548
10349636
11042159
11076861
11217851
12368295
12466851
12477932
12520002
12904583
14610273
14621295
15489334
16141072
16141073
16602821
16901266
16945627
17116694
17593974
17720696
17920055
18213582
18503048
18539921
18687675
18799693
19258013
20185795
20394677
20410206
20442248
20479257
20503373
20643830
20855470
21267068
21677750
21719793
22008794
22071102
22298771
22351753
22865881
23074159
23238718
23863478
23950901

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0060348  bone development
GO:0051216  cartilage development
GO:0002063  chondrocyte development
GO:0048706  embryonic skeletal system development
GO:0014846  esophagus smooth muscle contraction
GO:0032836  glomerular basement membrane development
GO:0003094  glomerular filtration
GO:0030201  heparan sulfate proteoglycan metabolic process
GO:0060384  innervation
GO:0001822  kidney development
GO:0008152  metabolic process
GO:0016525  negative regulation of angiogenesis
GO:0030336  negative regulation of cell migration
GO:0001937  negative regulation of endothelial cell proliferation
GO:0040037  negative regulation of fibroblast growth factor receptor signaling pathway
GO:0060686  negative regulation of prostatic bud formation
GO:0030513  positive regulation of BMP signaling pathway
GO:0030177  positive regulation of Wnt receptor signaling pathway
GO:0010575  positive regulation vascular endothelial growth factor production
GO:0040036  regulation of fibroblast growth factor receptor signaling pathway
GO:0006790  sulfur metabolic process
GO:0048010  vascular endothelial growth factor receptor signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0005783  endoplasmic reticulum
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0045121  membrane raft
GO:0005886  plasma membrane

Molecular Function

GO:0004065  arylsulfatase activity
GO:0005509  calcium ion binding
GO:0003824  catalytic activity
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0008449  N-acetylglucosamine-6-sulfatase activity
GO:0008484  sulfuric ester hydrolase activity