essential meiotic endonuclease 1 homolog 1 (S. pombe)

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Synonym

Eme1, Crossover junction endonuclease EME1, MGC106543, 6820428D13

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.80 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:96.40 eye:30.40 artery/aorta:- vein:- lymphnode:- peripheral blood:14.40 spleen:13.20 thymus:98.80 bone marrow:12.80 adipose:- bone:50.10 skin:55.40
GeneChip cerebrum:4.62 cerebellum:4.56 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:4.93 spine:4.89 retina:4.67 eye:5.13 artery/aorta:- vein:5.55 lymphnode:5.66 peripheral blood:- spleen:4.99 thymus:- bone marrow:7.58 adipose:4.87 bone:6.99 skin:5.03
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.36 vein:- lymphnode:0.94 peripheral blood:- spleen:2.16 thymus:1.35 bone marrow:- adipose:- bone:1.84 skin:0.97
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:130.90 placenta:27.60 prostate:- ovary:11.50 testis:36.90 heart:18.60 muscle:- esophagus:- stomach:65.50 intestine:- colon:-     liver/hepato:9.10        lung:-    bladder:- kidney:32.20 pituitary:12.90 thyroid/parathyroid:- adrenal gland:- pancreas:18.80 breast:16.30 salivary:-
GeneChip uterus:5.14 placenta:4.86 prostate:4.64 ovary:4.89 testis:6.06 heart:4.73 muscle:4.92 esophagus:- stomach:5.32 intestine:5.83 colon:- liver/hepato:5 lung:4.49 bladder:4.53 kidney:4.92 pituitary:5.14 thyroid/parathyroid:- adrenal gland:4.80 pancreas:5.84 breast:4.94 salivary:5.63
CAGE uterus:0.74 placenta:0.94 prostate:0.37 ovary:0.94 testis:1.48 heart:- muscle:- esophagus:- stomach:0.67 intestine:1.55 colon:0.93     liver/hepato:0    lung:0.31 bladder:0.18 kidney:- pituitary:0 thyroid/parathyroid:- adrenal gland:0 pancreas:0 breast:0.78 salivary:-
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_177752
Gene ID 268465
Unigene ID Mm.358937
Probe set ID 1435054_at  [Mouse430_2]
Ensembl ID ENSMUSG00000039055

Orthologous Gene

Human[2]  NM_001166131, NM_152463
Rat[1]  NM_001105830, NM_152463

Chromosomal Region

-

Gene Family (Interpro ID)

IPR006166  ERCC4 domain
IPR011335  Restriction endonuclease, type II-like, core

Link to Pubmed  (Pubmed ID)

10349636
10922068
11042159
11076861
11217851
12466851
12477932
14609959
14610273
15489334
16141072
16141073
17036055
18692478
18799693
21267068
21425081
21677750
22516201
24076219

Gene Ontology  (GO ID)

Biological Process

GO:0006310  DNA recombination
GO:0006281  DNA repair
GO:0006974  response to DNA damage stimulus

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0004519  endonuclease activity
GO:0016787  hydrolase activity
GO:0046872  metal ion binding
GO:0004518  nuclease activity