inhibitor of growth family, member 4

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Synonym

inhibitor of growth family, member 4, p29ING4, Inhibitor of growth protein 4, D6Xrf92, D6Wsu147e, Ing4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:10.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:64.30 eye:22.80 artery/aorta:- vein:- lymphnode:10.80 peripheral blood:14.40 spleen:- thymus:49.40 bone marrow:12.80 adipose:- bone:- skin:23.80
GeneChip cerebrum:8.13 cerebellum:8.61 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:7.76 spine:8.17 retina:7.86 eye:7.66 artery/aorta:- vein:8.55 lymphnode:8.68 peripheral blood:- spleen:8.50 thymus:- bone marrow:8.49 adipose:8.93 bone:8.06 skin:8.64
CAGE cerebrum:3.62 cerebellum:- brain stem:3.56 corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:3.40 retina:- eye:- artery/aorta:3.42 vein:- lymphnode:3.58 peripheral blood:- spleen:3.31 thymus:3.78 bone marrow:- adipose:- bone:3.21 skin:3.46
RNA-seq cerebrum:12.39 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:30.90 ovary:11.50 testis:317.80 heart:18.60 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:9.10        lung:-    bladder:- kidney:- pituitary:51.70 thyroid/parathyroid:- adrenal gland:- pancreas:18.80 breast:13.10 salivary:-
GeneChip uterus:9.28 placenta:9.63 prostate:8.59 ovary:8.64 testis:7.46 heart:7.90 muscle:8.32 esophagus:- stomach:8.70 intestine:8.75 colon:- liver/hepato:8.36 lung:8.23 bladder:8.86 kidney:8.41 pituitary:8.45 thyroid/parathyroid:- adrenal gland:8.04 pancreas:7.69 breast:8.92 salivary:8.27
CAGE uterus:3.99 placenta:3.86 prostate:3.97 ovary:3.64 testis:2.46 heart:- muscle:- esophagus:- stomach:3.91 intestine:3.50 colon:3.63     liver/hepato:3.42    lung:3.65 bladder:3.98 kidney:- pituitary:3.87 thyroid/parathyroid:- adrenal gland:3.51 pancreas:3.86 breast:3.78 salivary:-
RNA-seq uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:5.33 esophagus:- stomach:- intestine:- colon:-     liver/hepato:4.03        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-

Gene Information

IDs

Refseq ID NM_133345
Gene ID 28019
Unigene ID Mm.347910
Probe set ID 1460728_s_at  [Mouse430_2]
Ensembl ID ENSMUSG00000030330

Orthologous Gene

Human[11]  NM_001127582, NM_001127583, NM_001127584, NM_001127585, NM_001127586, NM_016162
Rat[1]  NM_001079887, NM_001127583, NM_001127584, NM_001127585, NM_001127586, NM_016162

Chromosomal Region

-

Gene Family (Interpro ID)

IPR019787  Zinc finger, PHD-finger
IPR001965  Zinc finger, PHD-type

Link to Pubmed  (Pubmed ID)

7482790
8889548
9811942
10349636
10725249
10922068
11042159
11076861
11217851
12466851
12477932
12520002
12904583
14595844
14610273
15489334
15618518
15782199
16141072
16141073
16602821
18287559
18799693
19250543
19521500
20059953
20211142
20412781
20534538
21267068

Gene Ontology  (GO ID)

Biological Process

GO:0006915  apoptosis
GO:0007049  cell cycle
GO:0007050  cell cycle arrest
GO:0016568  chromatin modification
GO:0006978  DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260  DNA replication
GO:0043966  histone H3 acetylation
GO:0043983  histone H4-K12 acetylation
GO:0043981  histone H4-K5 acetylation
GO:0043982  histone H4-K8 acetylation
GO:0008285  negative regulation of cell proliferation
GO:0045926  negative regulation of growth
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0043065  positive regulation of apoptosis
GO:0006473  protein amino acid acetylation

Cellular Component

GO:0000123  histone acetyltransferase complex
GO:0005634  nucleus

Molecular Function

GO:0046872  metal ion binding
GO:0035064  methylated histone residue binding
GO:0003713  transcription coactivator activity
GO:0008270  zinc ion binding